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Defining new standards for qPCR machines...Benefits of Automated Eluent Generation...Behind the Science, episode 7: Get Relax...

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Webcasts
Webcast - How to Optimize Sample Preparation Step Prior to ExtractionHow to Optimize Sample Preparation Step Prior to Extraction
Discover the benefits of bead-binding for sample preparation in this on demand webinar from Bertin Technologies.
Webcast - Innovative Benign-by-design Flow Chemistry Protocols: From Nanomaterials Synthesis to Biomass/Waste Valorization Innovative Benign-by-design Flow Chemistry Protocols: From Nanomaterials Synthesis to Biomass/Waste Valorization
On demand webinar from Professor Rafael Luque, Universidad de Cordoba.

Market Reports
Scientific News
Safe CO2 Storage Viable Following Tests
Successful trials in Australia have led to the discovery of an inexpensive method of stored CO2 monitoring underground.
Phosphorous Pollution Remains Major Issue
Phosphorus pollution of lakes is a major problem. Researchers now look to improve the state of the lakes, otherwise freshwater quality will suffer.
Detecting Pesticides, Nerve Gas With an Electronic Nose
Detecting pesticides and nerve gas in very low concentrations? An international team of researchers led by Ivo Stassen and Rob Ameloot from KU Leuven have made it possible.
Carbon Capture Breakthrough
Chemists from the University of York have developed a new, green, CO2 capture system with a focus around reducing large scale emissions.
Massive Helium Discovery a "Game Changer" for Medical Industry
A new development is gas exploration has yielded the discovery of a huge helium gas field, which could help relieve the dwindling supply.
NASA Study Explains Sea Ice Differences at Poles
NASA-led study uses satellite and environmental data to shed light on differences in sea ice formation between Arctic and Antarctic.
Wireless, Wearable Toxic-Gas Detector
Inexpensive sensors could be worn by soldiers to detect hazardous chemical agents.
Tracking The Aluminum Used To Purify Tap Water
Kobe University researchers demonstrate a new analysis method to measure the concentration of aluminium used to purify tap water.
Electronic Sensor Tells Dead Bacteria From Live
The sensor, which measures 'osmoregulation', is a potential future tool for medicine and food safety.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Business News
Funding for Advanced Water Testing Tech
MBio Diagnostics announces funding from the National Science Foundation to advance water toxin testing technology.
Metrohm USA Receives the Electrochemical Society Leadership Circle Award
Metrohm USA is proud to announce that it has received the Leadership Circle Award from The Electrochemical Society (ECS) recognizing ten consecutive years of membership.
Helsinki Chemicals Forum Examines the Relationship of Chemicals to the Circular Economy
Forum addresses economic development and sustainability with a particular emphasis on the opportunities and challenges the circular economy poses for chemicals regulation.
Lab Innovations Gears Up for 2016
Lab Innovations 2016 returns to the NEC, Birmingham, for its fifth edition. The show, which has established itself as the UK’s only event dedicated to laboratory professionals, will take place on 2 & 3 November 2016.
Helsinki Chemicals Forum Zeros in on The Circular Economy
Chemicals Management and Sustainable Chemistry Highlighted During Upcoming Conference in May
Xylem Analytics Enters Agreement with Lab Synergy
Company has announced agreement with Lab Synergy for expansion of customer solutions available through direct channels in North America.
Expansion of Xylem Analytics Customer Solutions
Expansion will support goals to expand geographically and accelerate growth.
TTIP and Chemical Regulations: Is Safety at Risk?
The Transatlantic Trade and Investment Partnership (TTIP) is a trade and investment deal between the EU and the US. It is a bi-lateral trade agreement that aims to reduce the regulatory barriers to trade. This article examines TTIP from a regulatory standpoint.
Field Pathogenomics a Defence Against Rust and Other 'Cereal Killers'
Leading scientists discuss rust prediction and prevention at Agri-Tech East Pollinator event.
Postnova Analytics Opens UK Office
Company has announced that it has opened a dedicated office to enhance local support for its growing base of UK customers.

Events
Event - Biodetection & Biosensors 2016
18 Oct 2016
Biodetection & Biosensors 2016 ...
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WWEM - Water, Wastewater & Env
02 Nov 2016
WWEM - Water, Wastewater & Env ...
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Lab Innovations 2016
02 Nov 2016
Lab Innovations 2016 ...
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BIT
04 Nov 2016
BIT's 5th Annual International ...
More Information

ePosters
Multiplexed Cell- and Bead-based Assays in a No-wash Format for Biologics Screening and Characterization
TTP Labtech Inc, One Kendall Square, Suite B2303, Cambridge MA 02139-1594, USA

Here we present the results generated from multiplexed no-wash protocols using TTP Labtech’s mirrorball, a laser scanning cytometer.
Development of a Homogenous RSV Neutralization Assay on the Mirrorball Fluorescence Cytometer: A Simple, Safe and Robust Approach for High-throughput Screening
TTP Labtech Ltd, Melbourn Science Park, Melbourn, Royston, Hertfordshire, SG86EE, UK.

Here we present the development and implementation of a simple RSV-neutralization assay on TTP Labtech’s mirrorball fluorescence cytometer.
Platform Agnostic Data Processing Routine for Targeted and Untargeted Metabolite Identification in Drug Discovery
1Advanced Chemistry Development, Inc. (ACD/Labs), 8 King Street East, Toronto, ON. M5C 1B5. Canada; 2ACD/Labs, Moscow, Russia

A discussion of a new informatics solution that addresses common challenges in metabolite identification and characterization--from LC/MS data processing and metabolites prediction to reporting and databasing of assembled biotransformation knowledge.
A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources
Biological Industries

An overview of a novel SF, XF differentiation system which enables achieving defined conditions for rapid generation of differentiated hMSCs towards tissue engineering and drug screening applications.
Molecular Abnormalities in Schizophrenia: Neurotransmission, Oxidative Stress, and Apoptosis
1Section of Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, London SW7 2AZ, U.K. 2

A multi-platform approach was employed to analyse distinct brain regions implicated in schizophrenia.
Accurate Mass Spectral Database: Harnessing the Power of High Performance Mass Spectrometry at Long Last
LECO Corporation, Moscow State University

Standard mixtures comprising of alkanes, PAHs, semivolatiles, and pesticides were analyzed using a high resolution time-of-flight (HRTOF) mass spectrometer—Pegasus GC-HRT (LECO Corporation, Saint Joseph,MI)—at 10 spectra-per-second (m/z40–300) in high resolution mode (25,000 at FWHH). The resulting chromatographic peaks were automatically found, deconvoluted, and curated into an Accurate Mass Library (AML).
Super-resolution single molecule localization microscopy of the exocytotic machinery underlying insulin secretion.
Heriot-Watt Univeristy

Single molecule imaging of the tSNARE proteins involved in insulin secretion.
Automated Sample Preparation of Whole Blood for Therapeutic Drug Monitoring and Diagnostics by LC-MS using a Commercial Autosampler
1 University of Applied Sciences and Arts Northwestern Switzerland FHNW, Institute for Chemistry and Bioanalytics , Gründenstrasse 40, 4132 Muttenz; 2 CTC Analytics AG; Industriestrasse 20, CH-4222 Zw

In this poster the parameters necessary to automatically prepare whole blood samples for online LC-MS applications in the field of diagnostics and TDM have been investigated. A strategy and the most important parameters are shown for the optimization of a PAL RTC autosampler
for the preparation of whole blood samples.
Development and Application of Quantitative Immunoassays for Major Milk Allergens Bos d 5 (β-lactoglobulin) and Bos d 11 (β-casein)
1. Indoor Biotechnologies, Ltd., Cardiff, Wales, UK. 2. INRA, Gif-sur-Yvette, France

In this study, we sought to develop accurate, sensitive and reliable assays that would enable quantification of multiple milk allergens.

Diagnosing Coral disease with Metabolomic Markers
NYUAD

Application of untargeted metabolomics for the identification of disease markers in corals
Application Notes
Rapid Point of use DNAble® Assay for Salmonella enterica using the Douglas Scientific® AmpliFire®
Douglas Scientific

With greater portability than real-time PCR instrumentation, the AmpliFire produces rapid and accurate results in the field or in the lab without cumbersome equipment or reagents. In a recent study, the AmpliFire® accurately detected the presence of Salmonella enterica using both purified genomic DNA and a crude sample preparation method, making it a powerful tool for point of use applications.
Automated Sample Preparation of 25-OH-Vitamin D3/D2 from Serum with the AC Extraction Plate and the Tecan Freedom EVO® for the quantification by LC-MS/MS
Tecan Group Ltd.

There is an increasing demand for the determination of Vitamin D status which is based on the quantification of the two metabolites 25-OH-Vitamin D3/D2. Numerous laboratories have moved from the use of immunoassay methods to liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) because of its specificity combined with high sensitivity. Moreover LC-MS/MS offers the potential for multianalyte determination which is required for Vitamin D status determination.
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Sodium, Potassium, Calcium and Magnesium in cooling water
Metrohm AG

This application note outlines the determination of sodium, potassium, calcium and magnesium in cooling water using cation chromatography with direct conductivity detection.
Optimization of Instrument Settings and Measurement Parameters for Kinetic Fluorometric and Luminometric Assays
Thermo Fisher Scientific

When fluorometric and luminometric assays are performed in microplate format, a high number of samples can be analyzed at a time. The speed of the reaction kinetics of the assay determines the requirements for the detection instrument and measurement parameters for achieving the best possible performance of the assay.
Turbidometric Growth Curve Measurements and Liquid Evaporation Studies with a Microplate Photometer
Thermo Fisher Scientific

The turbidity of a liquid sample is traditionally measured either with a nephelometer or a photometer. The measure of turbidity (also called optical density, OD) refers to the scattering of light from the particles of the measured sample. When measuring turbidity of a bacterial culture, the amount of scattered light is directly proportional to the number of bacterial cells in the sample.
Validated Luminometric DLR™ Reporter Gene Assay with Thermo Scientific Varioskan® Flash
Thermo Fisher Scientific

One of the most common luminometric assays is Dual Luciferase® Reporter Assay from Promega corp. This application note shows how this assay is performed with Varioskan Flash multitechnology microplate reader. The note includes the performance of the normal DLR assay and results from some tests showing important aspects of the basic behaviour and performance of the DLR™ chemistry. This paper describes the overall efficiency of the Varioskan Flash in the measurement of DLR assay.
Analysis of Inorganic Cations in Drinking and Waste Water by Cation Exchange Chromatography with Conductivity Detection
Cecil Instruments Ltd

Inorganic cations are significant indicators of the quality of drinking waters and their suitability for human consumption. They have important physiological effects and they alter the palatability of water.
Ultra Low Detection Limits for Inorganic Anions and Cations in Power Station Boiler Water Analysis
Cecil Instruments Ltd

Boilers used in power stations hold ultra pure water, the purity of that water needs to be determined by highly sensitive techniques. Ion Chromatography is a technique which offers high sensitivity.
Rapid Analysis of Polycyclic Aromatic Hydrocarbons in Seafood
Shimadzu

The recent Deepwater Horizon oil spill in the Gulf of Mexico created concerns over the safety of seafood that can get potentially contaminated with Polycyclic Aromatic Hydrocarbons (PAHs) from crude oil. The US Environmental Protection Agency identifies PAHs as critical pollutants harmful to human health. Some of these compounds are known carcinogens.
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