Corporate Banner
Satellite Banner
Food & Beverage Analysis
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Bruker Launches IMPACT HD Mass Spec Providing Exceptional Proteomic Results

Published: Tuesday, June 11, 2013
Last Updated: Tuesday, June 11, 2013
Bookmark and Share
Bruker’s IMPACT HD sets a new scientific benchmark of well over 8000 protein identifications from whole-proteome analysis, a record-breaking insight into trace species in complex biological samples.

At the 61st ASMS conference, Bruker has introduced exciting new High-Definition capabilities in proteomics and biomarker research.

Patented low-noise Captivespray nanoBooster™ ionization coupled with record high-speed digitization Qq-TOF technology and steered by intelligent acquisition software defines complex samples more sharply than ever before.

The novel High-Definition accurate mass spectrometer, impact HD™ is the latest innovation in Bruker’s UHR-TOF product line.

It opens up enhanced analytical performance levels for all applications where trace analysis from complex, high-background matrices is challenge - such as biomarker research, identification of impurities or residue screening.

Thanks to extreme sensitivity broad mass-transfer ion optics and fastest ever 50Gbit/sec sampling technology a dynamic range of 5 orders of magnitude is achieved in one second of LC time.

Wide dynamic range at high speed is a prerequisite for high-resolution detection of low-abundance compounds in sharp UHPLC peaks and permits direct quantitation without re-run.

The HD performance is directed by unique intelligent self-optimizing Instant Expertise™ software. MSMS acquisition parameters are dynamically adapted precisely to the incident sample, independent of sample amount or complexity, translating directly into higher productivity and expert-caliber results first time.

Bruker also introduces the CaptiveSpray nanoBooster™ which complements all Bruker LCMS instruments for new performance levels in proteomics and glycoanalysis.

The new version of Bruker’s established CaptiveSpray source employs a novel dopant-enriched gas ionization environment to boost sensitivity, enhance charge state and reduce background noise to drive up protein ID rates significantly.

The ability to engineer enhanced charge state is especially beneficial on Bruker’s amazon ETD ion trap in the structural analysis of glycopeptides by ETD.

The features ensure IMPACT HD delivers the fastest time-to-success for customers across a broad applications portfolio ranging from small molecule identification and characterization; food, forensic and environmental screening, metabolomics, proteomics to antibody analysis.

“Dynamic range really means something in your proteomics analysis when it can genuinely be delivered at UHPLC speeds” commented Carsten Baessmann Head of Applications Development “today we’re showing in a proteomics sample more than 8440 proteins at a false discovery rate (FDR) of better than 1% are identified from a combined 2D LC separation experiment with a CaptiveSpray nanoBooster™ - impact HD system.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Bruker’s NMR FoodScreener™ Laboratory Achieves ISO/IEC 17025 Accreditation
Bruker announced that its NMR FoodScreener™ laboratory for food authenticity and quality determination, located in Rheinstetten, Germany, has been granted ISO/IEC 17025 accreditation.
Monday, September 28, 2015
Using LC-MS to Analyse Sulfonamides in Food Grade Honey
Sulfonamides are one of a number of groups of chemicals whose presence in honey is limited by international regulations.
Tuesday, July 22, 2014
Bruker Reports 7% Revenue Growth in Q4
Bruker Corporation reported financial results for its fourth quarter and full year ended December 31, 2013.
Wednesday, February 19, 2014
Bruker Corporation Appoints Dr. Gilles Martin to its Board of Directors
Dr. Martin is Chairman and Chief Executive Officer of the Eurofins Scientific Group.
Monday, January 20, 2014
Scientific News
Feeding Babies Egg and Peanut May Prevent Food Allergy
The new analysis pools all existing data, and suggests introducing egg and peanut at an early age may prevent the development of allergy.
Food Colour Re-Evaluation Milestone
The re-evaluation of titanium dioxide marks the completion of the EFSA's re-evaluation of all food colours permitted for use in the EU before 2009.
Risks in Your Food
Researchers have developed a method to reliably detect allergenic substances in foods.
Dietary Selenium Content Linked to Cancer
Researchers have shown higher blood selenium levels are associated with reduced liver cancer risk.
Sensor Could Help Fight Bacterial Infections
The sensor can detect E.coli bacteria in 15-20 minutes over a wide temperature range, offering a fast and cost effective tests.
Chemical in Plastics Linked to Genital Abnormalities
Researchers have linked an endocrine-disrupting chemical to reproductive organ abnormalities in children.
Sharks Contain High Levels of Neurotoxins Linked to Alzheimer’s
Research team suggests restricting shark consumption to protect human health as shark fins & meat contain high levels of neurotoxins.
Investigating Bacteria in Raw Milk
A microbial study of milk trucks aims to improve dairy food safety and quality.
FDA Isolates Hepatitis A Outbreak Origin
The FDA and CDC are aiding the Hawaii Department of Health investigation into hepatitis A virus (HAV) infections linked to imported scallops.
MRSA – Just Add Salt
Scientists have discoved a new way to attack Staphylococcus aureus through salt content mechanisms
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!