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Determination of Metabolically Unstable Drugs in Blood by Heat-Stabilized DBS and LC-MS/MS
The aims of this work were to investigate drug stability prior to, during and after blood spot sampling, using procaine, prulofloxacine, esmolol, and acetylsalisylic acid as examples of drug compounds with limited stability and to compare conventional DBS sampling procedure with DBS sampling including heat stabilization.

Date Posted: 11/10/2013 09:41:22


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