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  Events - January 2013


2nd Stratified Medicine Conference

22 Jan 2013 - 23 Jan 2013 - Boston, MA, USA



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Stratified medicine has the potential to revolutionize medical care by utilizing an improved understanding of genetics and molecular biology. As a result, this will enable improved diagnostic tests, more precise diagnoses, greater predictability of disease course, and improved patient safety by selecting not only the right drug for a patient but also the appropriate dosage to reduce adverse effects.

ExL’s 2nd Stratified Medicine Conference will bring together the industry’s leading stratified and personalized medicine experts to provide you with unique take-home examples, case studies and multiple innovative strategies to implement stratified medicine initiatives within your own organizations.

By attending this conference, you will hear industry-specific case studies and examples including:

Pathways to partnership in therapeutic-diagnostic development

The future of translational research and stratified medicine Innovations in detecting molecular malfunctions impacting cancer research and 
therapy

The role of biomarkers and translational science in the discovery organization

Pursuing stratified medicine: via predictive biomarkers to enhance clinical decision 
making

The regulatory path to approval via stratified medicine Integrating clinical benefits with the economic implications

Examining the importance of pharmacokinetic biomarkers in early clinical 
development decision points

Stratifying patients for clinical trials based on molecular and clinical data

Examining the challenges of companion diagnostics in pharmaceutical development

Exploring models for industry / academia collaboration in stratified medicine

Benefit from industry participation from Pfizer, Merck, MedImmune, Johnson & Johnson, Novartis, Selventa, EMD Serono, Daiichi Sankyo, MIT, and many more personalized and stratified medicine innovators and experts.


 



Further information
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New Therapeutic Targets For Small Cell Lung Cancer Identified
Researchers at UTSW Medical Center have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.
Deciphering Inactive X Chromosomes
Untangling the Barr body of inactive X chromosomes valuable for understanding chromosome structure and gene expression.
Micro Disease-Detecting Senor Created
Researchers at McMaster University have created a microscopic disease-detecting sensor that can turn on to detect trace amounts of substances.
Liquid Biopsies Treating Ovarian Cancer
Researchers have discovered a promising monitor and treat recurrence of ovarian cancer. Detecting cancer long before tumours reappear.
Uncovering a New Principle in Chemotherapy Resistance in Breast Cancer
The NIH study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.
Understanding Treatment Resistant Melanoma
Researchers have determined how advanced melanoma becomes resistant; a development toward developing treatments.
Investigating ‘Black Box’ of Human Genetics
Investigations into inactive X chromosomes have shown unusual DNA repeat elements are essential for maintaining 3D structure.
Liquid Biopsies: DNA Size Matters
Study finds circulating tumour DNA can be distinguished from healthy DNA through fragment size identification.
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