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  Events - January 2013


2nd Stratified Medicine Conference

22 Jan 2013 - 23 Jan 2013 - Boston, MA, USA



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Stratified medicine has the potential to revolutionize medical care by utilizing an improved understanding of genetics and molecular biology. As a result, this will enable improved diagnostic tests, more precise diagnoses, greater predictability of disease course, and improved patient safety by selecting not only the right drug for a patient but also the appropriate dosage to reduce adverse effects.

ExL’s 2nd Stratified Medicine Conference will bring together the industry’s leading stratified and personalized medicine experts to provide you with unique take-home examples, case studies and multiple innovative strategies to implement stratified medicine initiatives within your own organizations.

By attending this conference, you will hear industry-specific case studies and examples including:

Pathways to partnership in therapeutic-diagnostic development

The future of translational research and stratified medicine Innovations in detecting molecular malfunctions impacting cancer research and 
therapy

The role of biomarkers and translational science in the discovery organization

Pursuing stratified medicine: via predictive biomarkers to enhance clinical decision 
making

The regulatory path to approval via stratified medicine Integrating clinical benefits with the economic implications

Examining the importance of pharmacokinetic biomarkers in early clinical 
development decision points

Stratifying patients for clinical trials based on molecular and clinical data

Examining the challenges of companion diagnostics in pharmaceutical development

Exploring models for industry / academia collaboration in stratified medicine

Benefit from industry participation from Pfizer, Merck, MedImmune, Johnson & Johnson, Novartis, Selventa, EMD Serono, Daiichi Sankyo, MIT, and many more personalized and stratified medicine innovators and experts.


 



Further information
Scientific News
Breast Cancer Cells Found To Switch Molecular Characteristics
Spontaneous interconversion between HER2-positive and HER2-negative states could contribute to progression, treatment resistance in breast cancer.
Some Breast Cancer Patients With Low Genetic Risk Could Skip Chemotherapy
Genetic test can help predict survival and guide treatment options.
Lose Weight, Escape the Eight: Weight-Based Cancer Risk
IARC has identified eight additional cancer sites linked to overweight and obesity.
Coffee Consumption Linked to Genes
Researchers have identified a gene that influences coffee consumption. The gene is thought to relate to caffeine breakdown.
Emerging Model of Cancer
Cancer acts cooperatively, making individual decisions but acting in unison; this insight is being used to create a computer model of cancer.
Biological Barcodes Using CRISPR
Using genome editing tools, researchers are getting closer to understand differentiation of various cell types during development.
Controlling DNA Repair
Scientists discover that DNA repair outcomes following CRISPR-Cas9 cleaving are non-random and can be harnessed to produce desired effects.
Demonstrating LNP Delivery of CRISPR Components
Intellia has presented data demonstrating in vivo gene editing ising liquid nanoparticles (LNPs) to deliver CRISPR/Cas9.
Gene Therapy Via Ultrasound
Research into a gene therapy approach called sonoporation could help combat heart disease and cancer.
Creating Embryos with 'Heteroplasmy'
New discovery in genetic research could lead to treatments for mitochondrial diseases.
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