Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>Events>This Event
  Events - November 2013


Drug-drug combinations made simple

06 Nov 2013 - 06 Nov 2013 - Webinar



Bookmark and Share


Date/Time: 6 November 2013, 4:00 PM CEST | 2:00 PM GMT | 10:00 AM EST | 7:00 AM PST

Drug screening for combinations or single agents can be demanding and tedious. At the Netherlands Cancer Institute Robotics and Screening Center (NRSC), potential drug combinations that either restore or enhance clinical response are selected based on large-scale genomic screening projects which combine genomic datasets including clinical data. The Institute’s HP D300 Digital Dispenser offers accurate, flexible and user-friendly experimental set-up for these combination studies, saving valuable time.

The NRSC uses an advanced technology platform to perform large-scale, high throughput screening projects with cell-based or biochemical assays. These screens enable researchers to identify novel targets for cancer therapy and understand the mechanism of action of novel drugs, as well as to identify resistance mechanisms and determine effective drug combinations for specific patient groups carrying defined genetic alterations.

In this presentation, the NRSC’s workflow for identification of drug combinations and follow-up drug synergy studies using the HP D300 will be presented.

About the speakers

Beijersbergen.gif
Roderick L. Beijersbergen, Associate Professor Division of Molecular Carcinogenesis and Head NKI Robotics and Screening Center.


Halonen.gif
Pasi Halonen, Post-doc Division of Molecular Carcinogenesis and NKI Robotics and Screening Center


Merlino.gif
Jessica Merlino, Product Manager HP D300, Tecan



Further information
Scientific News
Scientists Find Evidence That Cancer Can Arise Changes
Researchers at Rockefeller University have found a mutation that affects the proteins that package DNA without changing the DNA itself can cause a rare form of cancer.
Modified Microalgae Converts Sunlight into Valuable Medicine
A special type of microalgae can soon produce valuable chemicals such as cancer treatment drugs and much more just by harnessing energy from the sun.
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
Loss Of Y Chromosome Increases Risk Of Alzheimer’s
Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at risk of developing Alzheimer’s disease.
A Guide to CRISPR Gene Activation
A comparison of synthetic gene-activating Cas9 proteins can help guide research and development of therapeutic approaches.
Gene That Lowers Heart Attack Risk Identified
Individuals with a rare twelve-letter deletion from a gene on chromosome 17 have significantly reduced non-HDL cholesterol levels and a 35% lower than average risk of heart disease.
Testing Non-Breast/Ovarian Cancer Genes
Researchers have found that expanding gene panel beyond breast/ovarian cancer genes in these patients does not add any clinical benefit. Instead, testing has produced more questions than answers.
Myeloid-Derived Suppressor Cells Play Role in Tumor Growth
Researchers at Baylor College of Medicine have reported a new mechanism that helps cancer cells engage myeloid-derived suppressor cells.
Cancer Cells Coordinate to Form Roving Clusters
Rice University scientists identify ‘smoking gun’ in metastasis of hybrid cells.
Genes For Nose Shape Found
Genes that drive the shape of human noses have been identified by a UCL-led study.
Scroll Up
Scroll Down
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!