Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Hamilton Robotics and French Police Scientifique Publish Paper Describing Large-Scale Production of Genetic Profiles

Published: Wednesday, March 10, 2010
Last Updated: Wednesday, March 10, 2010
Bookmark and Share
More than 300,000 profiles have already been processed on the Hamilton platforms and stored in French Database.

Scientists from Hamilton Robotics and Institut National de la Police Scientifique in Lyon, France have published an article in the December issue of Forensic Science International describing the protocols and three-year track record of a large-scale system they developed.

The automated system has processed in duplicate and deposited more than 300,000 genotypes into the French Reference Sample Database. The system produces genetic profiles from buccal swab cells on FTA* cards. Initially designed to process 20,000 samples per month, the system’s capacity was recently doubled to 40,000 per month without adding hardware.  

The samples on FTA cards are punched directly into PCR plates and transferred onto the Hamilton MICROLAB® STAR liquid handling workstation. The Hamilton air displacement pipetting and CO-RE (Compressed O-Ring Expansion) technology ensure contamination-free FTA wash and PCR reaction setup. Microplates are then sealed and transferred to a post-PCR system for pooling into a 384-well format and denaturing. Samples are tracked throughout the process and data is transferred to a LIMS.

“This is one of the first large-scale automated systems for forensic DNA analysis with a demonstrable track record,” explained Laurent Baron Product Manager Forensics, of Hamilton. “The creation of genetic databases requires highly reliable and robust automation, which our air displacement technology makes possible.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Automation of Adherent Cell Culture Maintenance
Hamilton, Life & Brain and University of Bonn will jointly develop a system for the automated culture of primary cells, cell lines and embryonic stem cells.
Monday, May 14, 2007
Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
Discovered Through ‘Big Data’ Analysis
Researchers at the SBP have identified over 100 new genetic regions that affect the immune response to cancer.
New Therapeutic Targets For Small Cell Lung Cancer Identified
Researchers at UTSW Medical Center have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.
Deciphering Inactive X Chromosomes
Untangling the Barr body of inactive X chromosomes valuable for understanding chromosome structure and gene expression.
Micro Disease-Detecting Senor Created
Researchers at McMaster University have created a microscopic disease-detecting sensor that can turn on to detect trace amounts of substances.
Liquid Biopsies Treating Ovarian Cancer
Researchers have discovered a promising monitor and treat recurrence of ovarian cancer. Detecting cancer long before tumours reappear.
Uncovering a New Principle in Chemotherapy Resistance in Breast Cancer
The NIH study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.
Understanding Treatment Resistant Melanoma
Researchers have determined how advanced melanoma becomes resistant; a development toward developing treatments.
Investigating ‘Black Box’ of Human Genetics
Investigations into inactive X chromosomes have shown unusual DNA repeat elements are essential for maintaining 3D structure.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!