Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Life Technologies Partners with German Cancer Research Center to Create World-Class Genome Sequencing Facility

Published: Thursday, June 03, 2010
Last Updated: Thursday, June 03, 2010
Bookmark and Share
Life Technologies Corporation and the German Cancer Research Center (Deutsches Krebsforschungszentrum or DKFZ), today announced their collaboration to create the National High-Throughput Sequencing Center.

This exclusive partnership will create the largest sequencing facility in Germany and the first national sequencing center in Europe dedicated to systems biology.

The center will operate 10 SOLiD™ 4 hq systems acquired by DKFZ and will initially sequence 1000 whole human cancer genomes for Germany’s national contribution to the International Cancer Genome Consortium (ICGC).  The facility will be partially funded by the German Federal Ministry of Education and Research.

Systems biology is the study of an organism as an integrated and interacting network of genes, proteins and biochemical reactions that give rise to life.  Often, experiments in systems biology require precise measurements of cellular events over time and assess changes in DNA sequence, RNA transcription or genomic copy number.  Therefore, these experiments require substantially more sequencing throughput than experiments that are not examining such dynamic changes in cellular events.

“Our aim is to understand the dynamic complexity of cellular processes on both the DNA and RNA level and how slight perturbations of those pathways contribute to the development of diseases like cancer,” said Professor Roland Eils from DFKZ.  “Therefore, it is of the utmost importance to be able to obtain quantitative precise measurements.  We are confident that this collaboration with Life Technologies will help us generate the highest quality data possible using the SOLiD™ technology.”

The SOLiD™ System is used globally in experiments to better understand the genetic nature of diseases such as cancer, diabetes, neurological disorders and other diseases.  Its throughput, accuracy and flexibility allow researchers to generate the data they need for their experiments.
 
“Life Technologies is proud to be the technology partner of choice for this new and exciting sequencing center and to be working with DKFZ, a renowned institution in Germany in life science research devoted to studying the complexities of human diseases like cancer,” said Mark Stevenson, President and Chief Operating Officer for Life Technologies.  “This center will be the first facility that will systematically bring high-throughput sequencing technologically into systems biology applications on a large scale.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Oncogene Controls Stem Cells in Early Embryonic Development
In a process called diapause, many animal species delay the development of their embryos in order to ensure that their offspring is born at a possibly favorable time.
Thursday, February 18, 2016
New Gold Standard to Improve Cancer Genome Analysis
When various labs are asked to investigate cancer cell genomes in search of mutations, their results can sometimes show significant variations, a team of scientists from the International Cancer Genome Consortium (ICGC) found out in a worldwide interlaboratory test.
Monday, December 14, 2015
Tolerant Immune System Increases Cancer Risk
Researchers have found that individuals with high immunoCRIT ratios may have an increased risk of developing certain cancers.
Thursday, October 08, 2015
A Yardstick to Measure the Malignancy of Prostate Cancer
Researchers have been searching for regulatory proteins that change the epigenetic characteristics of prostate cancer cells.
Wednesday, December 10, 2014
Blocking Cancer Stem Cells in the Brain Prolongs Survival in Mice
Blocking the stem cell marker slow down the growth of aggressive human brain cancers.
Tuesday, May 27, 2014
Suspicions Confirmed: Common Cause for Brain Tumors in Children
An overactive signaling pathway is a common cause in cases of pilocytic astrocytoma, the most frequent type of brain cancer in children.
Tuesday, July 09, 2013
Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Cancer Gene-Drug Combinations Ripe for Precision Medicine
The study aims to expand the number of cancer gene mutations that can be paired with a precision therapy.
Targeting BRAF Mutations in Thyroid Cancer
Treating metastatic thyroid cancer patients harboring a BRAF mutation with vemurafenib showed anti-tumor activity in a third of patients.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
Cancer Related Immune Response Genes Uncovered
Researchers at the SBP have identified over 100 new genetic regions that affect the immune response to cancer.
New Therapeutic Targets For Small Cell Lung Cancer Identified
Researchers at UTSW Medical Center have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer.
Deciphering Inactive X Chromosomes
Untangling the Barr body of inactive X chromosomes valuable for understanding chromosome structure and gene expression.
Micro Disease-Detecting Sensor Created
Researchers at McMaster University have created a microscopic disease-detecting sensor that can turn on to detect trace amounts of substances.
Liquid Biopsies Treating Ovarian Cancer
Researchers have discovered a promising monitor and treat recurrence of ovarian cancer. Detecting cancer long before tumours reappear.
Uncovering a New Principle in Chemotherapy Resistance in Breast Cancer
The NIH study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!