Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cisbio Bioassays Launches Epigenetics Toolbox

Published: Thursday, September 27, 2012
Last Updated: Thursday, September 27, 2012
Bookmark and Share
Pioneer of HTRF® technology expands platform to address growing field of epigenetics therapeutic research.

Cisbio Bioassays has announced the launch of its epigenetics toolbox for use in drug discovery research.

Epigenetics is a crucial field of study for the pharmaceutical and biotechnology industries due to its large range of applications related to human health.

This epigenetics toolbox, which offers a robust and reliable resource for such studies and is based on HTRF® technology, was introduced in Europe at MipTec 2012 in Basel, Switzerland and will be released on October 1st in the United States at Discovery on Target 2012 in Boston, Massachusetts.

Cisbio Bioassays’ epigenetics toolbox is a selection of conjugates specifically developed by the company for epigenetics studies, in response to requests from pharmaceutical and biotechnology researchers for reagents that would help better understand how these events occur through epigenetic mechanisms and how they relate to multiple therapeutic areas and diseases such as metabolic, CNS and immune system disorders.

The toolbox works in combination with Cisbio Bioassays’ other HTRF-based reagents to provide a single, robust and easy-to-use technology for studying classes such as histone methylation and histone demethylation.

“Protein: protein interactions and modifications have long been front and center in drug discovery research and now epigenetics target classes have become highly sought after by researchers because of their broad span of applications,” said François Degorce, head of marketing and communications at Cisbio Bioassays.

Degorce continued, “Epigenetics has become one of Cisbio Bioassays’ core research programs in response to the high demand from clients for more specific study tools, like HTRF, that can be applied to this field. To meet this need, we will regularly implement new assays that allow for studying relevant enzymes and the way in which they function. In fact, our development of this first set of reagents parallels our global commitment to introducing novel tools to our growing catalogue, much as we have been doing with our kinase screening platform throughout the year.”

As part of the development of its kinase screening platform, Cisbio Bioassays has also launched two HTRF cellular kinase assays, Phospho-MEK1 and Phospho-MEK1/2.

These assays, designed for detecting and studying activated MEK when phosphorylated at Ser218 and 222 directly in whole cells, can be used for the investigation of the MAP kinase pathway and therefore the screening of potential anti-cancer therapeutic compounds.

Cisbio’s kinase screening platform now comprises 11 assays - Phospho-CREB (Ser133), Phospho-mTOR (Ser2448) and Phospho-EGFR were introduced in June 2012 - and additional kits are planned in the upcoming months.

All assays feature the benefits of HTRF technology: streamlined protocols, miniaturization and application to any phase of drug screening.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Cisbio Bioassays and IGF Launch CNS Drug Discovery Research Program
Cisbio Bioassays, member of IBA Group and global provider of HTRF® (homogenous time resolved fluorescence) technology and services to facilitate drug discovery, has announced the launch of the GluSense research and development program in partnership with the Functional Genomics Institute of Montpellier, France.
Tuesday, November 30, 2010
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
New Weapon in the Fight Against Blood Cancer
This strategy, which uses patients’ own immune cells, genetically engineered to target tumors, has shown significant success against multiple myeloma, a cancer of the plasma cells that is largely incurable.
Toxin from Salmonid Fish has Potential to Treat Cancer
Researchers from the University of Freiburg decode molecular mechanism of fish pathogen.
Study Finds Non-Genetic Cancer Mechanism
Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found.
Scientists Create CRISPR/Cas9 Knock-In Mutations in Human T Cells
In a project spearheaded by investigators at UC San Francisco, scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9.
Tracking Breast Cancer Before it Grows
A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes.
DNA Damage Seen in Patients Undergoing CT Scanning
Along with the burgeoning use of advanced medical imaging tests over the past decade have come rising public health concerns about possible links between low-dose radiation and cancer.
The Mystery of the Instant Noodle Chromosomes
Researchers from the Lomonosov Moscow State University evaluated the benefits of placing the DNA on the principle of spaghetti.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!