Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Empire Genomics Licenses First Known DNA Biomarker for Multiple Myeloma

Published: Thursday, November 29, 2012
Last Updated: Thursday, November 29, 2012
Bookmark and Share
Detection of gene abnormalities may help patients and physicians determine the best approach to treatment, improve survival rate and lower treatment costs.

Empire Genomics announced it has acquired an exclusive license for patent pending novel genomic biomarkers from Emory University for use in developing a molecular diagnostic test that could help satisfy a large unmet medical need in determining ideal therapeutic treatment for multiple myeloma patients.

Recent data point to certain genetic biomarkers that may identify which patients would benefit from receiving treatment with the various therapies opposed to those that receive no benefit. The team is embarking in a phase II biomarker driven clinical trial using this technology to validate its power to predict outcomes in new generations of MM drugs.

"Developing a clinically validated multiple myeloma cancer theranostic assay with informative data would represent a major breakthrough in improving disease management," said Leon Bernal-Mizrachi, M.D., Assistant Professor of Hematology and Medical Oncology, Emory University School of Medicine "It would fulfill an unmet medical need to help patients with multiple myeloma better plan treatment options that will help produce the best outcomes."

Multiple myeloma accounts for approximately 10% of blood based cancers, with an estimated 21,700 new cases and 10,710 deaths in the US in 2012. Multiple myeloma is a malignant blood cell cancer that is increasing in frequency in today's aging population. While advances in therapeutic treatments have improved the response rate, there are significant side effects to these very costly treatments.

Empire Genomics is commercializing a genetic test for multiple myeloma that will guide treatments and reduce health care costs, while sparing patients the negative consequences of treatments that may not be effective. This new diagnostic test will be the first DNA biomarker test to direct treatment of multiple myeloma. Empire will explore the use of this biomarker in lymphoma patients as well.

"This is a meaningful breakthrough in the area of personalized medicine and we are excited to work with Emory University and Dr. Bernal-Mizrachi to bring it to the market to help oncologists make more informed treatment decisions for this dreadful disease," said Anthony Johnson, CEO of Empire Genomics.

Empire Genomics, a leader in field of personalized medicine, will use this test and others in development to continue to support and accelerate clinical trials and the creation of cancer companion diagnostics for therapies. It is expected that this test will be employed in clinical trials in the future as well as launched through clinical labs in early 2013.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Empire Genomics and Reprogenetics Join Forces to Improve Preimplantation Genetic Diagnosis
The Companies announced data on successful use of new PGD technique to improve the identification of genetic and chromosomal abnormalities.
Tuesday, October 16, 2007
Scientific News
Long Telomeres Associated with Increased Lung Cancer Risk
Genetic predisposition for long telomeres predicts increased lung adenocarcinoma risk.
Expanding the Brain
A team of researchers has identified more than 40 new “imprinted” genes, in which either the maternal or paternal copy of a gene is expressed while the other is silenced.
Identifying a Key Growth Factor in Cell Proliferation
Researchers discover that aspartate is a limiter of cell proliferation.
Study Uncovers Target for Preventing Huntington’s Disease
Scientists from Cardiff University believe that a treatment to prevent or delay the symptoms of Huntington’s disease could now be much closer, following a major breakthrough.
The Genetic Roots of Adolescent Scoliosis
Scientists at the RIKEN Center for Integrative Medical Sciences in collaboration with Keio University in Japan have discovered a gene that is linked to susceptibility of Scoliosis.
A Gene-Sequence Swap Using CRISPR to Cure Haemophilia
For the first time chromosomal defects responsible for hemophilia have been corrected in patient-specific iPSCs using CRISPR-Cas9 nucleases
New Tool Uses 'Drug Spillover' to Match Cancer Patients with Treatments
Researchers have developed a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker (KAR) predicts what genetics are truly driving the cancer in any population of cells and chooses the best "kinase inhibitor" to silence these dangerous genetic causes of disease.
Understanding the Molecular Origin of Epigenetic Markers
Researchers at IRB Barcelona discover the molecular mechanism that determines how epigenetic markers influence gene expression.
New Tech Enables Epigenomic Analysis with a Mere 100 Cells
A new technology that will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer has been developed by researchers at Virginia Tech.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!