Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Life Technologies Introduces Two Bioinformatics Offerings for Cancer Researchers

Published: Monday, April 08, 2013
Last Updated: Monday, April 08, 2013
Bookmark and Share
Company has launched Oncomine® Gene Browser and Ion Reporter™ Oncomine® Workflow.

Life Technologies Corporation has announced the introduction of two bioinformatics offerings - Oncomine® Gene Browser and Ion Reporter™ Oncomine® Workflow - that will allow cancer researchers new avenues of access to one of the largest genomics databases available, compiled by the former Compendia Bioscience.

Both products will be featured in Life Technologies' booth (#2222) at the 2013 annual meeting of the American Association for Cancer Research (AACR 2013), April 6 - 10 in Washington, D.C.

Oncomine® Gene Browser
Oncomine® Gene Browser enables cancer researchers to characterize their genes of interest across multiple parameters, including gene expression, DNA copy number and mutation data, from thousands of cancer patients' genetic data (exomes and transcriptomes).

The Oncomine® Gene Browser consists of a simple, dynamic web portal and provides a comprehensive gene summary at a moderate price point.

It is ideal for researchers working with small numbers of genes and enables the survey of individual genes across thousands of de-identified clinical cases and dozens of different cancer types and subtypes.

The new product introduction exemplifies Life Technologies' commitment to offering high-value products in the bioinformatics space across a range of price options and demonstrates the company's ability to serve all customers in the cancer research space, including basic, translational and clinical scientists, as well as those working in the biotech and pharma industry.

"Oncomine® Gene Browser is a new product for the academic and smaller pharma scientist that will enable them to be competitive in research and drug development," said Dan Rhodes, head of medical bioinformatics for Life Technologies.

Rhodes continued, "These investigators will now have access to data that have been collected and curated over the course of a decade, drawing from hundreds of clinical studies and representing millions of dollars worth of experiments, which will allow them to design more focused experiments and make faster progress."

"Oncomine® Gene Browser constitutes a unique solution for scientists working in the drug discovery and companion diagnostics space," said Ronnie Andrews, president of Medical Sciences at Life Technologies.

Andrews continued, "When combined with Life's broad portfolio of instrument systems for cancer research, including our Ion Torrent semiconductor based sequencing system and AmpliSeq Cancer Panels, researchers now have an extremely robust system which will provide markedly enhanced selection criteria to more rapidly advance their research."

Ion Reporter™ Oncomine® Workflow
The Ion Reporter™ Oncomine® Workflow streamlines cancer research by combining its proven Oncomine® platform with Ion Reporter™ Software. It provides access to curated next generation sequencing data from 4,000 matched tumor and normal pairs and is designed to assist with interpreting variants from data obtained on the Ion Torrent™ semi-conductor sequencing platforms from Life Technologies.

Using the Ion Reporter™ Oncomine® workflow with Ion AmpliSeq™ cancer panels, such as the Cancer Hotspot Panel and the Comprehensive Cancer Panel, enables researchers to move from sample to sequence to driver mutations in a day, rather than weeks or months. The Ion Reporter™ Oncomine® Workflow will be available at no charge for an introductory period, making this premier cancer bioinformatics capability accessible to any scientist.

"This is a major advance because cancer sequencing experiments often yield hundreds of variants, among which only a small fraction are true cancer driver mutations," said Dan Rhodes, head of Medical Science Informatics for Life Technologies.

"Previously researchers were faced with cumbersome literature searches or complex bioinformatics approaches to discern drivers from passenger mutations. The thousands of patient tumor samples driving the Oncomine Analysis provide both context and confidence for the Gain of Function or Loss of Function classification. This allows any cancer researcher to immediately identify likely driver mutations in their sample."

Ion Reporter™ Software is a suite of bioinformatics tools that enables users to quickly identify and report on biologically relevant mutations. Ion Reporter™ Software streamlines data analysis by providing simple tools for mapping, calling and annotating variants. The Oncomine® platform is a product of Compendia Bioscience®, a preeminent cancer bioinformatics company, which was purchased by Life Technologies in October 2012.

"Next-generation sequencing of cancer samples identifies many potentially important variants, particularly if matched germline DNA is not sequenced in parallel," said Scott Tomlins, M.D., Ph.D., assistant professor, Department of Pathology, University of Michigan. "The addition of Oncomine® annotations to Ion Reporter™ Software provides the best way to prioritize those mutations that are likely cancer drivers, based on well-curated supporting evidence across cancer types."

Life Technologies acquired Compendia Bioscience® in October 2012. Data compiled by Compendia comprises one of the world's largest and most comprehensive sets of mutation profiles, gene expression data and cellular biomarkers that have been gathered from more than 71,000 cancer patients. Oncomine®, a web-based analytics tool, integrates high-throughput cancer profiling data across a large volume of cancer types that provides researchers with valuable insights into biology, regulation, pathways, drug response, and patient populations.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

KACST Partners with Life Tech in The Saudi Human Genome Program
Program aims to analyze 100,000 human genomes to identify the causes of disease in the population of the Kingdom of Saudi Arabia and the Arab world.
Monday, December 09, 2013
Life Technologies Awards Digital PCR Innovation Grants to Five Research Labs
The five Innovation Grant recipients in the Digital PCR Applications Grant Program was announced during the ASHG conference in Boston.
Thursday, October 24, 2013
Thermo Acquisition Approved by Life Technologies Stockholders
Company announced that its stockholders voted to adopt the previously announced merger agreement.
Thursday, August 22, 2013
Life Technologies Enters into an Exclusive License and Supply Agreement for Dynabead
Life Technologies has signed a long-term supply and exclusive licensing agreement with Novartis for immunotherapeutics involving T cells modified to express chimeric antigen receptors for the treatment of cancer.
Thursday, August 01, 2013
Life Technologies Announces Second Quarter 2013 Results
Revenue increased 1% excluding impact of currency.
Thursday, August 01, 2013
Life Technologies Signs Five-Year Agreement with the FDA
The agreement aims to accelerate and advance food safety testing of E. coli and Salmonella, two foodborne contaminants commonly associated with outbreaks and/or recalls.
Tuesday, July 30, 2013
Roswell Park Cancer Institute Purchases Six Ion Torrent Sequencers
Life Technologies Corporation announced that the new Center for Personalized Medicine at Roswell Park Cancer Institute has purchased four Ion Proton™ sequencers and two Ion Personal Genome Machine™ sequencers.
Thursday, February 21, 2013
Boston Children's Hospital and Life Technologies Launch Claritas Genomics, a Clinical Genomics Company
Spinoff venture will develop genomic sequencing solutions utilizing Ion Torrent technology for clinical applications.
Thursday, January 10, 2013
Life Technologies introduces Ion AmpliSeq™ Community Panels
Ion AmpliSeq™ Community Panels leverages the expertise of scientific thought leaders and the Ion Community to create gene panels for conditions ranging from cancer to inherited diseases.
Wednesday, November 07, 2012
Life Technologies Acquires Compendia Bioscience
Acquisition expands Life Technologies' ability to drive progress in personalized medicine
Sunday, October 14, 2012
Life Technologies Acquires Compendia Bioscience
Bioinformatics expertise will enable deeper engagement with established customer base of leading pharmaceutical companies.
Tuesday, October 09, 2012
Life Technologies Signs Collaborative Agreement with Structural Genomics Consortium
Pioneering joint venture releases 58 of 200 planned, highly-specific recombinant antibodies for epigenetic studies.
Thursday, July 19, 2012
Life Technologies Collaborate with University of North Texas Health Science Center
University of North Texas Health Science Center advances forensic research by investing in semiconductor DNA sequencing technology.
Thursday, June 21, 2012
SickKids Adopts Life Technologies' Ion Proton™ Sequencer to Launch New Centre for Genetic Medicine
Long-term partnership will focus on sequencing 10,000 genomes per year to revolutionize pediatric disease research in Canada.
Thursday, June 21, 2012
Life Technologies Teams with Universitry of North Texas
University Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology.
Thursday, June 21, 2012
Scientific News
Poor Survival Rates in Leukemia Linked to Persistent Genetic Mutations
For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival.
Searching Big Data Faster
Theoretical analysis could expand applications of accelerated searching in biology, other fields.
Growing Hepatitis C in the Lab
Recent discovery allows study of naturally occurring forms of hepatitis C virus (HCV) in the lab.
Inciting an Immune Attack on Cancer Cells
A new minimally invasive vaccine that combines cancer cells and immune-enhancing factors could be used clinically to launch a destructive attack on tumors.
Reprogramming Cancer Cells
Researchers on Mayo Clinic’s Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.
Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies
CHOP genomics expert leads analysis of genetic architecture, with eye on repurposing existing drugs.
Surprising Mechanism Behind Antibiotic-Resistant Bacteria Uncovered
Now, scientists at TSRI have discovered that the important human pathogen Staphylococcus aureus, develops resistance to this drug by “switching on” a previously uncharacterized set of genes.
How DNA ‘Proofreader’ Proteins Pick and Edit Their Reading Material
Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have discovered how two important proofreader proteins know where to look for errors during DNA replication and how they work together to signal the body’s repair mechanism.
Fat in the Family?
Study could lead to therapeutics that boost metabolism.
Tissue Bank Pays Dividends for Brain Cancer Research
Checking what’s in the bank – the Brisbane Breast Bank, that is – has paid dividends for UQ cancer researchers.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!