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IDT gBlocks™ Gene Fragments Used for Expanding Gene Diversity

Published: Monday, June 03, 2013
Last Updated: Monday, June 03, 2013
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Discover how Amyris is using gBlocks fragments to build biological factories.

Integrated DNA Technologies (IDT) has released the latest edition of their DECODED newsletter, which discusses IDT gBlocks™ Gene Fragments and their role in biological factories.

Using synthetic biology, biological factories culture genetically modified microorganisms selected to produce a renewable and sustainable source of a broad range of target molecules, including pharmaceuticals and biofuels.

Amyris, an industrial synthetic biology company, has developed a high-throughput pipeline for the rapid testing of thousands of genetically engineered yeast and bacterial strains for production of Biofene®, a renewable diesel replacement, as well as pharmaceuticals, polymers, flavors, and fragrances.

Important to this process has been the sourcing and use of gBlocks Gene Fragments, which have provided Amyris a timely solution for engineering new bacterial and yeast strains.

Dr Sunil Chandran, the Head of the Automated Strain Engineering group, explains “gBlocks Gene Fragments allow us to get our hands on novel genes or other DNA parts in less than a week”.

The use of IDT gBlocks has enabled Dr Chandran and his team to expand the genetic diversity of test strains without any significant time delay, thereby accelerating the critical ‘Design-Build-Test’ cycle.

With high sequence fidelity, gBlocks Gene Fragments can be designed up to 500 base pairs and can be easily introduced to a diverse and innovative range of biological applications. Access the complete article in the 3.1 issue of DECODED.

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