Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

20/20 GeneSystems Awarded $750,000 NCI Contract

Published: Wednesday, February 26, 2014
Last Updated: Wednesday, February 26, 2014
Bookmark and Share
Award will see 20/20 develop companion diagnostic for targeted therapies in kidney cancer.

20/20 GeneSystems, Inc. announces that the NCI has awarded the company a cost-sharing Phase II Small Business Innovation and Research (SBIR) contract to develop, optimize, and validate (analytically and clinically) a test to help predict whether a patient with advanced stage kidney cancer (renal cell carcinoma) is likely to benefit from anti-angiogenic therapy. The anticipated end result is a diagnostic test that will indicate to oncologists the appropriate treatment for patients. 

With an estimated 65,000 new cases in the US in 2013 kidney cancer represents 3% of all cancers yet the disease is the 6th leading cancer death, with an estimated 13,600 deaths in 2013. Kidney cancer does not exhibit any symptoms at an early stage it therefore often remains undetected until it is advanced. Advanced renal cell carcinoma does not respond to chemotherapy and radiation. Three types of treatments are currently used: immunotherapy, anti-angiogenic agents, and mTOR inhibitors and no treatment is effective in more than a fraction of patients. Kidney cancer can progress very rapidly. Once the cancer is detected it is important to select the right treatment as quickly as possible. 

“There is a large unmet clinical need for an assay to identify kidney cancer patients likely to respond or not respond to a particular therapy. The early results which 20/20 presented last year are very promising. The 20/20 test would help guide treatment decisions and strategies so we can provide the best informed care to our patients,” says Sandy Srinivas, MD, Associate Professor of Oncology at the Stanford University School of Medicine. “There is a definite need for a companion diagnostic to predict response to anti-angiogenic drugs as there are other targeted therapies, with other mechanisms of action, which may be more suitable”. 

The development of the proof of concept development was funded by Phase I SBIR contract HHSN261201000135C from the National Cancer Institute and private funds. 


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

20/20 GeneSystems Acquires Rights to Lung Cancer Screening Test
The Company intends to develop a diagnostic that would help identify lung cancer.
Tuesday, December 20, 2005
Scientific News
New CAR T Cell Therapy Using Double Target Aimed at Solid Tumors
Researchers at Penn University have described how antibody, carbohydrate combination could apply to range of cancer types.
Erasing Unpleasant Memories with a Genetic Switch
Researchers from KU Leuven and the Leibniz Institute for Neurobiology have managed to erase unpleasant memories in mice using a 'genetic switch'.
New Method Detects Telomere Length for Research into Cancer, Aging
UT Southwestern Medical Center cell biologists have identified a new method for determining the length of telomeres, the endcaps of chromosomes, which can influence cancer progression and aging.
Assessing the Effectiveness of Genome-Editing Technologies
Researchers have developed a cost-effective and rapid method for assessing edits generated by CRISPR-Cas9 and other genome-editing technologies.
New Cancer Drug Target Found in Dual-Function Protein
Findings from a study from TSRI have shown that targeting a protein called GlyRS might help to halt cancer growth.
Alzheimer's Genetics Point To New Research Direction
A University of Adelaide analysis of genetic mutations which cause early-onset Alzheimer’s disease suggests a new focus for research into the causes of the disease.
Contagious Cancers Are Spreading in Shellfish
Direct transmission of cancer among some marine animals may be more common than once thought, suggests a new study published in Nature by researchers at Columbia University Medical Center (CUMC).
Contagious Cancers Are Spreading in Shellfish
Direct transmission of cancer among some marine animals may be more common than once thought, suggests a new study published in Nature by researchers at Columbia University Medical Center (CUMC).
Fix for 3-Billion-Year-Old Genetic Error
Researchers at The University of Texas at Austin have developed a fix that allows RNA to accurately proofread for the first time.
Higher Frequency of Huntington's Disease Mutations Discovered
University of Aberdeen study shows that the gene change that causes Huntington's disease is much more common than previously thought.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!