Corporate Banner
Satellite Banner
Genomics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

New Application of TAP’s Automated Cell Culture System at AACR

Published: Saturday, April 05, 2014
Last Updated: Saturday, April 05, 2014
Bookmark and Share
Offers rapid production and consistent quality of NCI 60 cancer cell line panel.

TAP Biosystems has announced a new NCI 60 application for its CompacT SelecT™, a system that automates cell culture and processing in T-flasks and microplates. The details of the application, which will deliver a full NCI 60 panel within a working week, are available on Booth 1846 at the AACR.

On the booth, TAP Biosystems’ experts will explain how using an intelligently designed, simple, five-day workflow it is possible to maintain cancer cell line panels, such as the NCI 60, on a CompacT SelecT and also generate assay plates for each cell line during a working week, thus saving thousands of hours of manual cell culture processing tasks.

Pivotal to this workflow are the CompacT SelecT’s integrated cell counter and confluence measurement capabilities. The cell counter ensures seeding density is consistent and regularly scheduled confluence measurements reliably predict when cell lines will reach their ideal harvest conditions.

This allows each flask, irrespective of cell line, to be processed so that flasks are harvested at optimal confluence. Depending on seeding density required for assay plates, harvesting a single T-175 flask could produce sufficient cells for five to ten 96-well plates, as well sufficient cells for seeding new daughter flasks to maintain the cell line.

By linking sequences of work including expansion, media exchanges and plating the system can be set up and run to ensure production of consistent NCI 60 cell line panels, without the need for error prone manual cell culture. This allows researchers constant access to high quality assay-ready cells for research, screening or profiling activities.

Dr Dave Thomas, Product Manager at TAP Biosystems explained: “Maintaining the NCI 60 cell line panel is a very time consuming task. However, because it can be cultured in a common basal media, the reagent requirements are minimal and as doubling times for the majority of the cell lines allow the majority to be passaged on either a three or four day schedule this enabled us to devise a simple five day workflow for culturing and maintaining the entire panel on a single CompacT SelecT.”

Thomas added: “We’re look forward to meeting scientists on Booth 1846 and discussing how this application of the CompacT SelecT could significantly reduce cell culture time and resource demands for researchers, as well as improve the consistency of cells they use in their oncology programmes.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,400+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Understanding Female HIV Transmission
Glowing virus maps points of entry through entire female reproductive tract for first time.
Genetic Markers Influence Addiction
Differences in vulnerability to cocaine addiction and relapse linked to both inherited traits and epigenetics, U-M researchers find.
A lncRNA Regulates Repair of DNA Breaks in Breast Cancer Cells
Findings give "new insight" into biology of tough-to-treat breast cancer.
Detection of HPV in First-Void Urine
Similar sensitivity of HPV test on first void urine sample compared to cervical smear.
Shape Of Tumor May Affect Whether Cells Can Metastasize
Illinois researchers found that the shape of a tumor may play a role in how cancer cells become primed to spread.
Computational Model Finds New Protein-Protein Interactions
Researchers at University of Pittsburgh have discovered 500 new protein-protein interactions (PPIs) associated with genes linked to schizophrenia.
MicroRNA Pathway Could Lead to New Avenues for Leukemia Treatment
Cancer researchers at the University of Cincinnati have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.
Analysis of Dog Genome will Provide Insight into Human Disease
An important model in studying human disease, the non-coding RNA of the canine genome is an essential starting point for evolutionary and biomedical studies – according to a new study led by The Genome Analysis Centre (TGAC).
New Insights into Gene Regulation
Researchers have solved the three-dimensional structure of a gene repression complex that is known to play a role in cancer.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,400+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!