Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Development of Oral Cancer Diagnostic Receives Backing

Published: Tuesday, July 22, 2014
Last Updated: Tuesday, July 22, 2014
Bookmark and Share
Zilico Ltd has received funding from the Technology Strategy Board, the UK’s innovation agency.

Zilico Ltd has begun development work on a medical device which uses Electrical Impedance Spectroscopy (EIS) in the detection and diagnosis of oral cancer following funding from the Technology Strategy Board, the UK’s innovation agency.  

The two awards are from the Biomedical Catalyst Feasibility and Smart Funds. The funds will help support an in-depth analysis of the UK market, deliver a product specification for an oral diagnostic device and a protocol for a multi-centre trial.

The funding builds on the proof-of-concept study that was recently presented and is part of a wider development programme leading to a multi-centre trial. The awards will help support development projects worth £160k.

Zilico’s lead product ZedScan uses its proprietary EIS technology to detect dysplasia and cancer of the cervix. As oral cancer follows a similar neoplastic pathway to that of the cervix, EIS can be used to detect changes in the oral epithelium as cells progress from normal to precancerous and then to cancerous.

The University of Sheffield’s Professor of Oral Medicine, Martin Thornhill, presented on the use of EIS in the detection and diagnosis of oral cancer and dysplasia to the most influential group of oral medicine experts in America last year.

Professor Thornhill’s presentation, Use of Impedance Spectroscopy to Detect Potentially Malignant Oral Lesions, was delivered at the 67th Annual Meeting of the American Academy of Oral Medicine (AAOM) in San Antonio, Texas. The study on 50 patients was the result of a collaboration between the University of Sheffield, Sheffield Teaching Hospitals NHS Foundation Trust and Zilico Ltd.

The presentation abstract was published in the Oral Surgery, Oral Pathology, Oral medicine and Oral Radiology Journal in September 2013.  The full paper describing the study has been accepted for publication in the peer-reviewed Journal of Nanomedicine.

Zilico Chief Executive Sameer Kothari said: “We are delighted to have secured this funding, which will allow us to build on the proof-of concept study and positive feedback the data received at last year’s AAOM.

“We are now well placed to further develop the device and assess it in a multi-centre clinical study. There is a clear clinical need for a more accurate diagnostic in the patient pathway.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
New Gene Therapy for Vision Loss From a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Five New Genetic Variants Linked to Brain Cancer Identified
The biggest ever study of DNA from people with glioma – the most common form of brain cancer – has discovered five new genetic variants associated with the disease.
Predictive Model for Breast Cancer Progression
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
Fatty Liver Disease and Scarring Have Strong Genetic Component
Researchers say that hepatic fibrosis, which involves scarring of the liver that can result in dysfunction and, in severe cases, cirrhosis and cancer, may be as much a consequence of genetics as environmental factors.
Specific Variations in RNA Splicing Linked to Breast Cancer
Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors. Targeting these changes could potentially lead to therapies for some forms of breast cancer.
Finding Links and Missing Genes
A catalogue of large-scale genetic changes around the world.
Scientists Test New Gene Therapy for Vision Loss from a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Gene Expression: A Snapshot of Stem Cell Development
New genes found that regulate development of stem cells.
Assessing Cancer Patient Survival and Drug Sensitivity
RNA editing events another way to investigate biomarkers and therapy targets.
A Natural History of Neurons
Diverse mutations reveal lineage of brain cells.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos