Sigma, a division of Sigma- Aldrich Corporation has announced that the U.S. Patent and Trademark Office granted the Company U.S. Patent Number 6,942,964, entitled "Tracer Reagents that Enhance Reaction-Product Analysis," covering the array of direct-load RED enzymes already being offered in Sigma's PCR product line.
REDTaq™ products are a blend of various DNA polymerases combined with an inert red dye. The dye allows quick visual confirmation of enzyme addition and reaction homogeneity.
The sample can also be loaded directly onto an agarose gel for electrophoresis following PCR. The red dye has no effect on downstream applications.
"Our RED enzymes have been successful as an added convenience and time-saver to the research community," said Keith Jolliff, Director of Strategic Marketing in the Biotechnology Business Unit at Sigma-Aldrich.
"This patent adds to our technology portfolio and expands our leadership in life sciences and high technology."
Sigma claims that, the RED enzyme product line covers all areas of PCR including routine amplification, hot start, long and accurate, and genomic DNA amplification.
The enzymes come in both a stand-alone format as well as a ReadyMix™ formula for added convenience.