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Thursday, April 24, 2014
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High-throughput analysis of protein formulations by DLS
Sophia Kenrick and Daniel Some

High-throughput analysis of protein formulations by Dynamic Light Scattering (DLS): thermal stability, colloidal stability and a thermal anomaly in the colloidal stability parameter D1

Digital microphotographic atlas of the adult zebrafish cerebellum
Kristen Lee, Megan Landy, Ashton Cline, Christopher Corbo, and Zoltan Fulop

Sagittal, coronal and horizontal, one micron thick plastic (semithin) sections of adult zebrafish (Danio rerio) brain were photographed in 40X. The sections were then photomontaged together using in Adobe Photoshop CS5 Extended Version 12.0 to make the photographic atlas.

The Effects of Dimethylphthalate on the Viability and Development of Drosophila melanogaster
Sara Mfarrej, Dr. Heather Cook, Dr. Donald Stearns, Dr. Zolton Fulop

My research studies the effect of dimethylphthalate (DMP), a putative endocrine disruptor, on the viability and development of the model organism Drosophila melanogaster.

Analytical Pipetting of Serum
John Thomas Bradshaw, PhD, Leah Flumerfelt, Richard H. Curtis, PhD, Rachel Parshley

Many types of chemical and biological analyses are based upon analytical techniques involving accurate delivery of liquid components. Pipetting tools have become commonplace especially in many biological and pharmaceutical laboratories. While these tools are familiar to many, their operational differences when pipetting different types of solutions are often over-looked.

Targeted cancer therapy based on blocking the expression of genes and small doses of oxaliplatin.
Bavykin A.S.1, Korotaeva A.A.1, Poyarkov S.V.2, Syrtsev A.V.1, Karpukhin A.V.1

The major drawbacks of the prescribed chemotherapy, are still remain the significant side effects and drug - resistance. Even targeted chemotherapy by means of specific antibodies do not always help to solve these complications. Our purpose was to identify potential biological targets associated with the development of drug resistance and to develop a specific method of suppressing the viability of cancer cells exposed to low doses of standard chemotherapy.

Cloud Point Extraction of Metal Oxide Nanoparticles in Water Samples Identified by Raman Spectroscopy and Quantified by Atomic Absorption Spectroscopy
Yanxiao Ma, Dr. Andrew F. Callender

Nanoparticles that are widely used in commercial products pose a threat to human health and the environment. This project proposes a cheaper and more effective method to identify and quantify metal oxide nanoparticles in water samples.

Cloud Point Extraction of Metal Oxide Nanoparticles in Water Samples Identified by Raman Spectroscopy and Quantified by Atomic Absorption Spectroscopy
Yanxiao Ma, Dr. Andrew F. Callender

Nanoparticles that are widely used in commercial products pose a threat to human health and the environment. This project proposes a cheaper and more effective method to identify and quantify metal oxide nanoparticles in water samples.

New Sorbent from Agro-industrial Waste and its Potential Use in 17ß-Estradiol and 17α-Ethynylestradiol Removal
Suzimara Rovani*, Éder C. Lima, Renato Cataluña, Andreia N. Fernandes

In recent years, the increasing introduction of new chemicals in the market, and the development of more accurate analytical methods, added a variety of endocrine disruptors compounds (EDC). Even though they are found in very low concentrations (range of ng L-1) there is still a lack of knowledge about long-term risks of EDC for non-target organisms as well as for human health.

Droplet Microfluidics for 3D Epithelial Cell Culture
Monika Dolega (Pyzalska), Xavier Gidrol, Nathalie Picollet-D’hahan

The challenge facing 3D cell culture today is to adapt current models to a systems biology approach - in particular, to enable RNA interference-based screens to study the effects of the microenvironment on cellular function.

Droplet Microfluidics for 3D Epithelial Cell Culture
Monika Dolega (Pyzalska), Xavier Gidrol, Nathalie Picollet-D’hahan

The challenge facing 3D cell culture today is to adapt current models to a systems biology approach - in particular, to enable RNA interference-based screens to study the effects of the microenvironment on cellular function.

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Showing Results 1 - 10 of 211
Scientific News
Muscle Weakness Seen in Alcoholism Linked to Mitochondrial Repair Issues
Scientists found evidence that chronic heavy alcohol use affects a gene involved in mitochondrial repair and muscle regeneration.
Fast Way to Measure DNA Repair
Test analyzing cells’ ability to fix different kinds of broken DNA could help doctors predict cancer risk.
Gene Linked to Excess Male Hormones in Female Infertility Disorder
Discovery by NIH-supported researchers may lead to diagnostic test, treatment.
Unexpected Protein Partnership has Implications for Cancer Treatment
Scientists have identified a macrophage that works together in response to cancer drugs to increase inflammation in a way that may alter tumor growth.
Targeting Cancer with a Triple Threat
MIT chemists design nanoparticles that can deliver three cancer drugs at a time.
Breakthrough Profiling Technology to Improve Cancer Treatment on a Personalized Basis
New research paper published in the peer reviewed journal PLOS ONE.
Blocking DNA Repair Mechanisms Could Improve Brain Cancer Therapy
The findings were published April 7 in Nature Communications.
Study Identifies Growth Factor Receptors That May Prompt the Spread of Lung Cancer
Preventing lung cancers from metastasizing to other parts of the body could provide benefit for patients against the leading cause of cancer death.
Cancer’s Thirst For Copper Can Be Targeted
Drugs used to block copper absorption for a rare genetic condition may find an additional use as a treatment for certain types of cancer.
An Integrated Approach to Clinical Genetics Research
OGT’s new whitepaper explores the next stage of molecular testing.
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