|Does the increase of exosomal microRNAs reflect an activated immune system in melanoma?|
Nina Koliha, Florian S. Dreyer , Jochen Dindorf , Andreas Bosio, Andreas S. Baur , and Stefan Wild
Cutaneous malignant melanoma is a form of skin cancer that accounts for 65% of skin cancer-related deaths. The incidence increases continuously, and while early detection leads to nearly 100% survival rates, the mortality raises to greater than 80% for patients with advanced disease.
|Stealth-Adapted Viruses and Viteria: Insights into Virus Construction, Replication and Potential Therapies|
W. John Martin
There is an increasing incidence of diseases with accompanying signs and symptoms of brain damage. These include neurological and psychiatric illnesses, childhood behavioral disorders, and such common conditions as chronic fatigue, Gulf War Syndrome, so-called “chronic Lyme disease”, and many cancers. Altogether, these diseases have an enormous social impact.
|Novel Nucleosomics Serum Biomarkers for the Detection of Colorectal Cancer|
S Holdenrieder, Y Dharuman, J Standop, M Herzog, N Trimpop, K Hettwer, K Simon, Steffen Uhlig and Jake Micallef
As colorectal cancers are often detected at late tumor stages when prognosis of the patients is poor, powerful blood-based biomarkers are needed for earlier detection. In recent years it has become clear that epigenetic changes to chromatin and its constituent nucleosomes are associated with carcinogenesis and elevated levels of nucleosomes are present in the blood of cancer patients.
|A novel DNA amplification method based on silicon microring resonator for rapid detection of genetic alteration in the point-of care (POC) field of cancers|
Nucleic acid testing plays a critical role in molecular diagnosis[1-2]. Due to the low amounts of DNA obtained in clinical samples, the amplification of DNA is an essential step in most NAT methods .
|Hypothesis of an Existence of a Reverse Pathway (Rp) which Passes Genetic Information from Polypeptide Antigens to Ig Genes in B-Lymphocytes|
Victor J. Alexander
Results of this research will bring new more effective treatment methods of many immune related diseases, including cancer.
|Oral Health Management of a Patient with 47 XYY Syndrome|
Dr Altaf H Shah, Prof. Amjad H Wyne and Prof. Rita Khounganian
The 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46.
|The Challenges of Relieving Cancer Pain: A Literature Review|
This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.
|Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital|
M Alkhusheh, H Asalieh, N Smith
Following the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March.
|Identification and Characterization of Strain Specific Drug Target by Subtractive Genome Analysis of Methicillin Resistance Staphylococcus aureus|
Kiran Saeed and Reaz Uddin
This study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology.
|Kidney Genes Expression in Hypertensive ISIAH Rats|
The present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.
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