Oral Health Management of a Patient with 47 XYY Syndrome Dr Altaf H Shah, Prof. Amjad H Wyne and Prof. Rita KhounganianThe 47XYY syndrome is an aneuploidy of sex chromosomes, where a human male receives an extra Y-chromosome making a total of 47 instead of the usual 46. |  | |
The Challenges of Relieving Cancer Pain: A Literature Review Rayna PatelThis study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence. |  | |
Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital M Alkhusheh, H Asalieh, N SmithFollowing the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March. |  | |
Identification and Characterization of Strain Specific Drug Target by Subtractive Genome Analysis of Methicillin Resistance Staphylococcus aureus Kiran Saeed and Reaz UddinThis study aimed to identify and characterize strain specific essential protein targets, which will eventually help in the identification of druggable proteins in two strains of MRSA by using different Bioinformatic tools and databases. We adopting a subtractive genome approach within the domain of Computational Biology. |  | |
Kidney Genes Expression in Hypertensive ISIAH Rats Tatyana PylnikThe present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.
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Automated Genomic DNA QC Ensures High Quality Data from Downstream Workflows Arunkumar Padmanaban, Ruediger Salowsky, Delphine Rabiller and Donna McDade WalkerThe success of several genomics study depends primarily on the quality of starting material, which in most cases is the genomic DNA. The quality and quantity of the extracted genomic DNA affects the downstream applications like microarray studies, library constructions and gene expression studies. |  | |
High-Throughput Analysis of DNA Samples using the D1K ScreenTape Assay and the Agilent 2200 TapeStation System Arunkumar Padmanaban, Ruediger Salowsky, Adam IncheRecent advances in genomics demands to look at a wealth of genetic information in a short period of time. DNA analysis using slab gel electrophoresis and capillary electrophoresis are widely being used as a QC step in next generation sequencing and microarray studies. However, often these techniques lack the speed and involve more manual steps to perform the assay. |  | |
FDG PET/CT Utility in Gynecologic Malignancies: A comprehensive review of anatomy, pathways of metastatic spread and scan findings Nicholas Plaxton, MD, Aruna Polsani, MD, Raghuveer Halkar, MD, Karen Godette, MD, Barron, Bruce, MDOur objective was to review the five major gynaecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy. |  | |
FDG PET/CT Characteristics of Adrenal Benign and Malignant Lesions Nicholas Plaxton, MD, Raghuveer Halkar, MD, Bruce Barron, MDWe selected FDG PET/CT cases with strong key representative findings to help illustrate benign and malignant adrenal lesions. Tabular review of PET SUV values, Hounsfield units and lesion size in the different cases will be discussed. |  | |
Hot Start dNTPs – Pushing the Limits of PCR Tony Le, Hidalgo Ashrafi, Sabrina Shore, Victor Timoshchuk, Natasha Paul, Richard Hogrefe, Inna Koukhareva, Alexandre LebedevHot Start dNTPs are a distinct approach that employs modified nucleoside triphosphates with a thermolabile protecting group. This modification blocks low temperature primer extension and is released at higher temperatures to allow for more specific DNA polymerase incorporation. |  | |
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