Satellite Banner
Technology Networks Header
Saturday, November 29, 2014
Technology Networks
 
Register | Sign in
Home Page>Posters

  Posters

Automation of a Generic Fluorescence Methyltransferase Activity Assay
X. Amouretti, P. Brescia, P. Banks, G. Prescott, Meera Kumar

Epigenetic processes are attracting considerable attention in drug discovery as their fundamental roles in controlling normal cell development and contributions to disease states become more clearly defined. This work combines a fluorescence-based assay with liquid handling and dispensing instrumentation and a multi-mode reader which can be used to monitor the biological activity of the histone methyltransferase (HMT) G9a, a model system.

Automation of a Novel Cell-Based ELISA for Cell Signaling Pathway Analysis
Wendy Goodrich, Peter Banks, Ron Osmond, Antony Sheehan

Monitoring and quantifying cell signaling pathways is critical for understanding the behavior of cell processes and many disease states. Monitoring and quantifying cell signaling pathways is critical for understanding the behavior of cell processes and many disease states.

Efficacy of Using a Combination Microplate Washer for Vacuum-Based DNA Sequencing Reaction Cleanup
Wendy Goodrich, Jason Greene, Mary Louise Shane

The ability to determine the specific pattern of base pairs in DNA molecules is an indispensable part of contemporary molecular biology. This poster demonstrates how the vacuum filtration module available on the BioTek 405 Touch effectively cleans contaminating artifacts from DNA sequencing reactions, which wil contribute to the genomic workflow typical of many molecular biology laboratories and core facilities.

Improving Cell-Mediated Cytotoxicity Assessment through the Use of an Automated Luminescent ADCC Assay
Brad Larson, Sumant Dhawan, Shalini Wadwani, and Peter Banks

Assays that can assess the ability of a biosimilar to act in a manner similar to the original biologic have seen increased interest. This poster describes the use of a non-radioactive luminescent chemistry to simplify the assay process and provide improved data quality.

Expression of Pluripotency-determining Factors in in vitro Fertilized Buffalo Embryos and Embryonic Stem Cells
T Anand, D Kumar, M S Chauhan, and P Palta

The POU octamer-binding domain transcription factor Oct-4, Stage-specific embryonic antigens (SSEAs), and Tumor rejection antigens (TRAs), are developmentally regulated during early embryogenesis.

UBS109, a novel curcumin analogue, promotes apoptosis in Head and Neck cancer cells through activating death receptor signaling pathway
Shujue Lan1,3, Min Heui Yoo1, Yuhong Du1,3, Terry Moore4 , Shijun Zhu2, Mamoru Shoji2, Georgia Chen2, Dong Shin2, Fadlo Khuri2, Dennis Liotta4, James P. Snyder4, Haian Fu1,2,3

UBS109, a new curcumin analogue, exhibited a potent anticancer activity, inhibiting colony formation and cancer cell growth in vitro, and tumor growth in a xenograft animal model in vivo. 2. UBS109 rapidly blocks the NF-?B signaling pathway through the

Visualizing the Dynamic Epigenome
Lydia Steiner (1,2), Thimo Rohlf (2), Joerg Galle (2), Hans Binder (2), Lydia Hopp (2), Henry Wirth (2), Sonja Prohaska (1,2)

A method is presented to visualize genome-wide information from epigenetic data. It is capable to integrate additional information. Applied to mouse data consisting of H3K4, H3K27, and H3K9 trimethylation for 3 different celltypes, the dynamic behavior and interplay was investigated.

Repurposing Drugs for the Treatment of Multi-Drug Resistant Breast Cance
David Monaghan, Rachel Griffin, Amie Regan, Enda O’Connell, Howard Fearnhead

In this study, the Johns Hopkins Clinical Compound Library, containing approximately 1,500 FDA and foreign-approved clinical compounds, was used to screen a multi-drug resistant, triple negative breast cancer cell line for drug sensitivity.

Genome sequenicng and analysis of the emerging pathogen Corynebacterium ulcerans
Eva Trost, Andreas Tauch

Sequencing of two C. ulcerans isolates and identification of a noval putative virulence factor

<< 8 9 10 11 12 13 14 >>
Showing Results 101 - 110 of 261
Scientific News
Gene Therapy Provides Safe, Long-Term Relief for Patients with Severe Hemophilia B
Gene therapy pioneered by St. Jude Children’s Research Hospital, University College London and the Royal Free Hospital provides men with hemophilia B reliable relief from the bleeding disorder.
Two Studies Identify A Detectable, Pre-Cancerous State In The Blood
Findings pave way for new lines of cancer research focused on detection and prevention.
A Link between DNA Transcription and Disease-Causing Expansions Which Lead to Hereditary Disorders
A Tufts University study explores the relationship between transcription and the expansions of DNA repeats.
New Study Reveals Why Some People May be Immune to HIV-1
Natural genetic variation in a protective antiviral enzyme holds promise for new therapies.
Amazing Feet Of Science: Researchers Sequence The Centipede Genome
What it lacks in genes, it certainly makes up for in legs: the genome of the humble centipede has been found to have around 15,000 genes – around 7,000 fewer than a human.
New Device Could Make Large Biological Circuits Practical
Innovation from MIT could allow many biological components to be connected to produce predictable effects.
How A Mutant Gene Can Cause Deafness
Scientists at The Scripps Research Institute (TSRI) have discovered how one gene is essential to hearing, uncovering a cause of deafness and suggesting new avenues for therapies.
Precisely Off The Mark
Possible cause discovered for failure of targeted liver cancer therapies.
Schizophrenia May be Triggered by Excess Protein
Neuroscientist Bonnie Firestein says too much causes abnormalities in brain development.
Brain-dwelling Worm in UK Man's Head Sequenced
Tapeworm removed from UK resident's brain reveals genetic secrets of an elusive Far East parasite.
Skyscraper Banner
Skyscraper Banner
Follow TechNetcom1 on Twitter
Technology Networks Ltd. on LinkedIn
Go to LabTube.tv