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LOCATION OF LOCI FOR RESISTANCE TO MYCOSPHAERELLA GRAMINICOLA, PLANT HEIGHT AND HEADING DATE THROUGH GENOME-WIDE ASSOCIATION MAPPING IN WHEAT
Guillermo Gerard1,2, Analía Sanabria1,3, María Rosa Simón1, Ulrike Lohwasser4, Andreas Börner4

Markers for resistance to septoria leaf blotch, heading date and plant height were found in a population of 96 genotypes through genome-wide association mapping DArT-based,

Analysis of the genomic structure of a wheat NIL population segregating for resistance to glume blotch with a 90k ILLUMINA SNP chip
Javier Sanchez-Martin1, Simon Krattinger1, Margarita Shatalina1,2, Thomas Wicker1 and Beat Keller1*

Analysis of the genomic structure of a wheat NIL population segregating for resistance to glume blotch with a 90k ILLUMINA SNP chip

Analysis of Imported Children's Toys for Heavy Metals
Patricia Atkins, Huifang Lang, William Driscoll

Children’s consumer products have been an active focus for study and regulation due to their ability to expose infants and children to potentially damaging and dangerous chemicals.

Intact Protein LC-MS: How to Overcome the Challenges?
Robert van Ling, Evert-Jan Sneekes, Sebastiaan Dolman, Laurent Rieux, Mauro DePra, Christian Ravnsborg, Dafydd Milton, Remco Swart

Purpose: Facilitate intact protein LC-MS without compromising performance.
Methods: Construct prototypes of integrated column and sprayer dedicated for intact protein separations and compare performance.
Results: Three prototypes have been directly compared and all showed good protein separations, each with their unique area of strength.

Targeted cancer therapy based on blocking the expression of genes and small doses of oxaliplatin.
Bavykin A.S.1, Korotaeva A.A.1, Poyarkov S.V.2, Syrtsev A.V.1, Karpukhin A.V.1

The major drawbacks of the prescribed chemotherapy, are still remain the significant side effects and drug - resistance. Even targeted chemotherapy by means of specific antibodies do not always help to solve these complications. Our purpose was to identify potential biological targets associated with the development of drug resistance and to develop a specific method of suppressing the viability of cancer cells exposed to low doses of standard chemotherapy.

Cloud Point Extraction of Metal Oxide Nanoparticles in Water Samples Identified by Raman Spectroscopy and Quantified by Atomic Absorption Spectroscopy
Yanxiao Ma, Dr. Andrew F. Callender

Nanoparticles that are widely used in commercial products pose a threat to human health and the environment. This project proposes a cheaper and more effective method to identify and quantify metal oxide nanoparticles in water samples.

Cloud Point Extraction of Metal Oxide Nanoparticles in Water Samples Identified by Raman Spectroscopy and Quantified by Atomic Absorption Spectroscopy
Yanxiao Ma, Dr. Andrew F. Callender

Nanoparticles that are widely used in commercial products pose a threat to human health and the environment. This project proposes a cheaper and more effective method to identify and quantify metal oxide nanoparticles in water samples.

New Sorbent from Agro-industrial Waste and its Potential Use in 17ß-Estradiol and 17α-Ethynylestradiol Removal
Suzimara Rovani*, Éder C. Lima, Renato Cataluña, Andreia N. Fernandes

In recent years, the increasing introduction of new chemicals in the market, and the development of more accurate analytical methods, added a variety of endocrine disruptors compounds (EDC). Even though they are found in very low concentrations (range of ng L-1) there is still a lack of knowledge about long-term risks of EDC for non-target organisms as well as for human health.

Droplet Microfluidics for 3D Epithelial Cell Culture
Monika Dolega (Pyzalska), Xavier Gidrol, Nathalie Picollet-D’hahan

The challenge facing 3D cell culture today is to adapt current models to a systems biology approach - in particular, to enable RNA interference-based screens to study the effects of the microenvironment on cellular function.

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Showing Results 121 - 130 of 320
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New gene therapy could save millions of people suffering from muscle wasting disease.
Mutations in DNA-Repair Genes Found in Advanced Prostate Cancers
New findings indicate that nearly 12% of male advanced prostate cancer sufferers have inherited mutation in DNA-repair genes.
Ice Bucket Challenge Instrumental in Gene Discovery
Donations from the ALS Ice Bucket Chellenge allowed for the largest-ever study of inherited ALS, which identified a new ALS gene.
Triple-Action Therapy Patch Shows Promise
Patch that delivers drug, gene, and light-based therapy to tumor sites shows promising results in mice.
Cancer Gene-Drug Combinations Ripe for Precision Medicine
The study aims to expand the number of cancer gene mutations that can be paired with a precision therapy.
Targeting BRAF Mutations in Thyroid Cancer
Treating metastatic thyroid cancer patients harboring a BRAF mutation with vemurafenib showed anti-tumor activity in a third of patients.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
Cancer Related Immune Response Genes Uncovered
Researchers at the SBP have identified over 100 new genetic regions that affect the immune response to cancer.
New Therapeutic Targets For Small Cell Lung Cancer Identified
Researchers at UTSW Medical Center have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer.
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