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New Gene Therapy for Vision Loss From a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Five New Genetic Variants Linked to Brain Cancer Identified
The biggest ever study of DNA from people with glioma – the most common form of brain cancer – has discovered five new genetic variants associated with the disease.
Predictive Model for Breast Cancer Progression
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
Fatty Liver Disease and Scarring Have Strong Genetic Component
Researchers say that hepatic fibrosis, which involves scarring of the liver that can result in dysfunction and, in severe cases, cirrhosis and cancer, may be as much a consequence of genetics as environmental factors.
Specific Variations in RNA Splicing Linked to Breast Cancer
Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors. Targeting these changes could potentially lead to therapies for some forms of breast cancer.
Finding Links and Missing Genes
A catalogue of large-scale genetic changes around the world.
Scientists Test New Gene Therapy for Vision Loss from a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Gene Expression: A Snapshot of Stem Cell Development
New genes found that regulate development of stem cells.
Assessing Cancer Patient Survival and Drug Sensitivity
RNA editing events another way to investigate biomarkers and therapy targets.
A Natural History of Neurons
Diverse mutations reveal lineage of brain cells.

A Polycomb-Based Switch Underlying Quantitative Epigenetic Memory
Andrew Angel, John Innes Centre, UK, speaking at Epigenetics 2011.

Cancer Methylome Profiling using Methyl-DNA Capture
Dr Arjen Brinkman, Radboud University Nijmegen (NL), speaking at Next-Gen Sequencing Europe 2011.

A Systematic Investigation of Candidate Breast Cancer Progression-Associated Biomarkers Identified from Omic Screens: Leveraging Antibody-Based Proteomics
Prof. William Gallagher, Chief Scientific Officer at OncoMark, speaking at Advances in Microarray Technology 2011.

RNA-Seq for High Throughput Clinical Studies
Wenzhong Xiao, Assistant Professor of Bioinformatics, Massachusetts General Hospital, speaking at Next-Gen Sequencing Congress 2011.

Genome-scale Quantitative Tumour Proteomics for Cancer Biomarkers Discovery
Metodi Metodiev, Lecturer/Director of Proteomics Unit, University of Essex, speaking at European Biomarkers Summit 2011.

Single Cell Genomics: Accessing the Genomes of Uncultivated Microbes
Mary-Jane Lombardo, Research Scientist, J. Craig Venter Institute, speaking at Next-Gen Sequencing Congress 2011.

Genomics of Bacterial Pathogen Strain Variation
Timothy Read, Associate Professor, Emory University School of Medicine, speaking at Next-Gen Sequencing Congress 2011.

Using Next-Gen Sequencing to Uncover Patterns of Allele-Specific Expression
Sergio Baranzini, Associate Professor, University of California, San Francisco, speaking at Epigenetics World Congress 2011.

The Epigenetic Regulation of microRNA Genes and Their Role in Cell Invasion and Motility in Human Melanomas
Ranjan Perera, Associate Professor, Sandford Burnham Medical Research Institute, Speaking at Epigenetics World Congress 2011

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