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FDA Announces New Warning on Plavix: Avoid Use with Prilosec/Prilosec OTC

Published: Wednesday, November 25, 2009
Last Updated: Wednesday, November 25, 2009
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Patients should avoid using the stomach acid reducer Prilosec/Prilosec OTC (omeprazole) with the anti-clotting drug Plavix (clopidogrel), the U.S. Food and Drug Administration warned on Nov. 17. New data suggest that when patients take both Prilosec and Plavix, Plavix’s ability to block platelet aggregation (anti-clotting effect) may be reduced by about half. “Both of these drugs, when used properly, provide significant benefits to patients.” said Mary Ross Southworth, Pharm.D., of the Div


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