Corporate Banner
Satellite Banner
Genotyping & Gene Expression
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Plexpress and MediSapiens Launch OncoTRAC™ Gene Expression Service

Published: Tuesday, October 02, 2012
Last Updated: Tuesday, October 02, 2012
Bookmark and Share
Digital gene discovery integrated with targeted validation and in-depth analysis.

The companies have launched the new OncoTRAC™ Gene Expression Service, which takes advantage of MediSapiens’ extensive IST Online Gene Expression Database to facilitate the rapid, reliable identification of relevant genes of interest. After this initial discovery phase, the Plexpress FAST TRAC Gene Expression Analysis technology is used to assay the expression of a hand-selected 30-gene panel in a large number of samples.  The unique combination of these two complimentary approaches presents a complete solution from gene discovery through to validation and in-depth study, across a wide range of drug development, biomarker discovery and life science research applications.

Tommi Pisto, CEO of MediSapiens, commented: “With a database of over 20,000 samples and 300 million data points, our MediSapiens IST Online Gene Expression Viewer is the world’s largest unified gene expression database. The new OncoTRAC Service will allow users to leverage this data to discover new genes and then investigate their biological relevance.” Visualizing a gene’s function across all tissues and exploring relationships between expression and disease, the database allows the straightforward integration of proprietary data, whilst strict normalization also allows the comparison of results from a wide spectrum of studies. Exploration and identification of the most relevant genes of interest from a pool of samples of various cancer types, treatment-response and disease grades are subsequently compared with expression in healthy tissue, providing a knowledge-based discovery approach.

CEO of Plexpress, Dr Jari Rautio, said: “TRAC is the ideal technology for following up genomic discovery using the IST Online Gene Expression Viewer, as it allows the multiplex analysis of up to 30 genes in hundreds to thousands of samples. In this way, researchers can really investigate the biology of their system in considerable depth, without sacrificing the number of genes they can assay in each sample.” The other benefits of the fully automatable TRAC process include increased assay speed, as well as reduced technical variation, hands-on time and assay cost when compared with similar methods such as qPCR and microarray analysis. While TRAC offers the flexibility to create custom gene panels, pre-validated catalogue libraries are also available for specific applications such as ADME-Tox studies, ready for rapid, ‘off-the-shelf’ utilization.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Plexpress Secures $2.3M to Commercialize TRAC High-Content Gene Expression Analysis Platform
Company targets applications including companion diagnostics and ADMET.
Thursday, April 19, 2012
Scientific News
Liquid Biopsies: Utilization of Circulating Biomarkers for Minimally Invasive Diagnostics Development
Market Trends in Biofluid-based Liquid Biopsies: Deploying Circulating Biomarkers in the Clinic. Enal Razvi, Ph.D., Managing Director, Select Biosciences, Inc.
Cell Aging Slowed by Putting Brakes on Noisy Transcription
Experiments in yeast hint at ways to extend life of some human cells.
Women’s Immune System Genes Operate Differently from Men’s
A new technology reveals that immune system genes switch on and off differently in women and men, and the source of that variation is not primarily in the DNA.
Long Telomeres Associated with Increased Lung Cancer Risk
Genetic predisposition for long telomeres predicts increased lung adenocarcinoma risk.
Expanding the Brain
A team of researchers has identified more than 40 new “imprinted” genes, in which either the maternal or paternal copy of a gene is expressed while the other is silenced.
Study Uncovers Target for Preventing Huntington’s Disease
Scientists from Cardiff University believe that a treatment to prevent or delay the symptoms of Huntington’s disease could now be much closer, following a major breakthrough.
The Genetic Roots of Adolescent Scoliosis
Scientists at the RIKEN Center for Integrative Medical Sciences in collaboration with Keio University in Japan have discovered a gene that is linked to susceptibility of Scoliosis.
A Gene-Sequence Swap Using CRISPR to Cure Haemophilia
For the first time chromosomal defects responsible for hemophilia have been corrected in patient-specific iPSCs using CRISPR-Cas9 nucleases
How a Kernel Got Naked and Corn Became King
Ten thousand years ago, a golden grain got naked, brought people together and grew to become one of the top agricultural commodities on the planet.
New Tool For Investigating RNA Gone Awry
A new technology – called “Sticky-flares” – developed by nanomedicine experts at Northwestern University offers the first real-time method to track and observe the dynamics of RNA distribution as it is transported inside living cells.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!