Corporate Banner
Satellite Banner
Genotyping & Gene Expression
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

PPMI Expands to Investigate Genetic Causes of Parkinson’s

Published: Wednesday, February 26, 2014
Last Updated: Wednesday, February 26, 2014
Bookmark and Share
PPMI will now also seek to study individuals with genetic mutations associated with Parkinson’s disease.

The Parkinson’s Progression Markers Initiative (PPMI), The Michael J. Fox Foundation’s landmark biomarkers clinical study, has expanded again; this time to learn more about the genetics of Parkinson’s disease (PD). In addition to groups currently enrolled in the study, PPMI will now also seek to study individuals with genetic mutations associated with Parkinson’s disease. In particular, PPMI seeks to understand the connection between PD onset and having a mutation in the LRRK2 gene – the single most common genetic contributor to Parkinson’s known to date.

Play a Part in PPMI:

Genetic traits are passed down through generations of families, and some ethnic groups have a higher presence of LRRK2 mutations in the gene pool than others. Because of this, PPMI is seeking individuals who meet either of the following criteria:

  • People with PD who are of Eastern European (Ashkenazi) Jewish, North African Berber, or Basque ancestry
  • People without PD who are related to someone with PD AND who are of Eastern European (Ashkenazi) Jewish, North African Berber, or Basque ancestry

Individuals who meet either of these criteria may be eligible to receive genetic counseling and testing at no cost to determine if they may qualify to participate in PPMI.

Studies of the genetics of Parkinson’s disease have revolutionized the pursuit of a “disease-modifying” treatment—a therapy that can slow or stop the progression of PD. Studying the genetics of Parkinson’s disease can speed progress toward treatments that would benefit everyone with the disease, even those with a non-genetic form of PD. PPMI needs volunteers to participate in this critical research.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Michael J. Fox Foundation Awards $2.4 Million for Validation of Nine Promising Therapeutic Targets for Parkinson's Disease
The annual MJFF program will provide intellectual and financial resources to help push potential PD drug targets forward toward clinical trials.
Friday, July 18, 2008
Scientific News
Liquid Biopsies: Utilization of Circulating Biomarkers for Minimally Invasive Diagnostics Development
Market Trends in Biofluid-based Liquid Biopsies: Deploying Circulating Biomarkers in the Clinic. Enal Razvi, Ph.D., Managing Director, Select Biosciences, Inc.
Cell Aging Slowed by Putting Brakes on Noisy Transcription
Experiments in yeast hint at ways to extend life of some human cells.
Women’s Immune System Genes Operate Differently from Men’s
A new technology reveals that immune system genes switch on and off differently in women and men, and the source of that variation is not primarily in the DNA.
Long Telomeres Associated with Increased Lung Cancer Risk
Genetic predisposition for long telomeres predicts increased lung adenocarcinoma risk.
Expanding the Brain
A team of researchers has identified more than 40 new “imprinted” genes, in which either the maternal or paternal copy of a gene is expressed while the other is silenced.
Study Uncovers Target for Preventing Huntington’s Disease
Scientists from Cardiff University believe that a treatment to prevent or delay the symptoms of Huntington’s disease could now be much closer, following a major breakthrough.
The Genetic Roots of Adolescent Scoliosis
Scientists at the RIKEN Center for Integrative Medical Sciences in collaboration with Keio University in Japan have discovered a gene that is linked to susceptibility of Scoliosis.
A Gene-Sequence Swap Using CRISPR to Cure Haemophilia
For the first time chromosomal defects responsible for hemophilia have been corrected in patient-specific iPSCs using CRISPR-Cas9 nucleases
How a Kernel Got Naked and Corn Became King
Ten thousand years ago, a golden grain got naked, brought people together and grew to become one of the top agricultural commodities on the planet.
New Tool For Investigating RNA Gone Awry
A new technology – called “Sticky-flares” – developed by nanomedicine experts at Northwestern University offers the first real-time method to track and observe the dynamics of RNA distribution as it is transported inside living cells.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!