Corporate Banner
Satellite Banner
Genotyping & Gene Expression
Scientific Community
Become a Member | Sign in
Home>News>This Article

Keck Foundation Grant Awarded to UC Davis Researcher

Published: Monday, March 10, 2014
Last Updated: Monday, March 10, 2014
Bookmark and Share
Grant will help fund biomedical project, "In Vivo 3D Imaging Using Bioluminescent Gene Reporters and MRI."

The W.M. Keck Foundation's Medical Research Program has presented a grant for $1 million to Angelique Louie, a professor and vice chair of the UC Davis Department of Biomedical Engineering. The grant will help fund her project "In Vivo 3D Imaging Using Bioluminescent Gene Reporters and MRI," which she is undertaking in collaboration with Yohei Yokobayashi, an associate professor also in the Department of Biomedical Engineering; and Jared Shaw, an associate professor in the Department of Chemistry.

"The project proposes novel technology that will facilitate the detection of gene expression in deep, opaque tissues," Louie explained. "With such technology, we'll be able to apply the power of noninvasive imaging to myriad new biomedical applications."

"We're grateful for the Keck Foundation's support," said Enrique J. Lavernia, dean of the UC Davis College of Engineering. "The advancement of cutting-edge technology requires our researchers to push the envelope: to take risks and try new approaches. Such daring often won't be embraced by government funders or foundations, and I applaud the Keck Foundation for its devotion to bold ventures that can have a positive impact on the entire world."

"I'm equally thankful for the Keck Foundation's appreciation for high-risk, innovative research," Louie echoed. "This funding will play a significant role in providing personnel and resources that will be crucial to the success of our project."

Louie earned an undergraduate degree in electrical engineering at UC Davis, and then developed an affinity for biomedical applications while studying fiber optics during her master's degree work at UCLA. She obtained a doctorate in 1994 at UC Irvine's Beckman Laser Institute, where she concentrated on the biomedical side of optical imaging with lasers. Post-doc studies took place at Cal Tech, where she worked in imaging and the development of enzymes inhibitors; this led to a project involving the creation of contrast agents for imaging.

Louie then investigated academic options and quickly became intrigued by the new, up-and-coming imaging department at UC Davis. She joined the College of Engineering's Department of Biomedical Engineering in 2002, which has proven to be an excellent fit.

She has continued her work with imaging techniques and the design of probes to characterize molecular phenomena in diseased and normal states, with the goal of helping clinicians better understand what causes — and how to prevent — cardiovascular disease, retinal degeneration and tumor formation. She's particularly interested in the monitoring of heart disease, in order to detect vulnerable arterial plaques at risk for rupture before they can cause a heart attack or stroke.

Outside the lab, Louie is director of the UC Davis Beckman Scholars Program, which stimulates, encourages and supports research activities by exceptionally talented undergraduate students in the fields of chemistry, biochemistry, and the biological and medical sciences. She also is a fellow of the American Institute of Medical and Biological Engineering, and she recently completed a term as an elected member of the board of directors for the Biomedical Engineering Society.

The Keck Foundation grant is part of the university’s first comprehensive fundraising campaign — The Campaign for UC Davis — which has raised $1.071 billion from 106,184 donors and is scheduled to conclude on May 31, 2014.

The W.M. Keck Foundation was established in 1954 by William Myron Keck, founder of the Superior Oil Company. Keck envisioned a philanthropic institution that would provide far-reaching benefits for humanity, with a mandate to encourage pioneering discoveries in science, engineering and medical research. In the area of education, the foundation also supports undergraduate programs that promote inventive approaches to instruction and the effective involvement of students in research.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

UC Davis "Lab on a Chip" Measures Heart Disease Risk
New test mimics artery conditions, detects inflammatory cells linked with atherosclerosis and myocardial infarction.
Thursday, August 08, 2013
Scientific News
Genetic Basis of Fatal Flu Side Effect Discovered
A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a recent study.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Mathematical Model Forecasts the Path of Breast Cancer
Chances of survival depend on which organs breast cancer tumors colonize first.
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Personalized Drug Screening for Multiple Myeloma Patients
A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
New Way to Force Stem Cells to Become Bone Cells
Potential therapies based on this discovery could help people heal bone injuries or set hardware, such as replacement knees and hips.
Promise of Newborn Stem Cells to Revolutionize Clinical Practice
In this article Shweta Sharma, PhD, discusses the potential of an Umbilical Cord Blood bank as an untapped source of samples for research and clinical trials.
New Anti-Malarial Drug Screening Model
University of South Florida researchers demonstrate novel chemogenomic profiling to identify drug targets for the most lethal strain of malaria.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos