Corporate Banner
Satellite Banner
Genotyping & Gene Expression
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Malvern Reports on the Publication of the 1000th Peer-reviewed Paper to Cite NanoSight’s NTA

Published: Wednesday, April 16, 2014
Last Updated: Tuesday, April 15, 2014
Bookmark and Share
Nanoparticle Tracking Analysis made measuring size easier and more accurate.

Malvern Instruments reports on the publication of the 1000th peer-reviewed paper to cite the company’s NanoSight Nanoparticle Tracking Analysis, NTA. Entitled “Fumed Silica Nanoparticle Mediated Biomimicry for Optimal Cell-Material Interactions for Artificial Organ Development,” it was authored by the research team of Professor Alexander Seifalian from University College London.

Alexander Seifalian is Professor of Nanotechnology and Regenerative Medicine at UCL Centre for Nanotechnology and Regenerative Medicine within the Division of Surgery and Interventional Science at University College London, UK. His research focus is on the development of human organs using nano composite materials and stem cells as well as treatment of cancer using nanoparticles.

With nanoparticles requiring rapid and repeatable measurement, Professor Seifalian selected Malvern’s NanoSight Nanoparticle Tracking Analysis (NTA) system. Previous to this, he had used techniques including scanning electron microscopy (SEM) and atomic force microscopy (AFM) but found that NTA made measuring size easier and more accurate.

Professor Seifalian’s paper, "Fumed Silica Nanoparticle Mediated Biomimicry for Optimal Cell-Material Interactions for Artificial Organ Development” published in the Journal of Macromolecular Biosciences (WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim), was the 1000th peer-reviewed item to be published where results from NTA are cited. In the paper, a fumed silica nanoparticle mediated procedure of scaffold functionalization is described which can be potentially adapted with multiple bioactive molecules to induce cellular biomimicry in the development of human organs. The proposed nanocomposite materials are already in patient use for implants including the world’s first synthetic trachea, tear ducts and coronary and vascular bypass grafts.

Nanoparticle Tracking Analysis detects and visualizes populations of nanoparticles in liquids down to 10 nm, dependent on material, and measures the size of each particle from direct observations of diffusion. Additionally, NTA measures concentration while a fluorescence mode differentiates suitably-labelled particles within complex background suspensions.

This real-time data gives insight into the kinetics of protein aggregation and other time-dependent phenomena in a qualitative and quantitative manner. NTA has a growing role in biodiagnostics, being proven in detection and speciation of extracellular vesicles.

NanoSight NTA systems are part of Malvern’s extensive portfolio of solutions for the characterization of nanomaterials.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Big Genetics in BC: The American Society for Human Genetics 2016 Meeting
Themes at this year's meeting ranged from the verification, validation, and sharing of data, to the translation of laboratory findings into actionable clinical results.
Making It Personal
Cancer vaccine linked to increased immune response against leukemia cells.
Protein-Based “Cancer Signature” Uncovered
Researchers investigated the expression of ribosomal proteins in human tissues and discovered a cancer type specific signature which could be used to predict the progression of the disease.
Blood-brain Barrier on a Chip
Researchers from Vanderbilt University have developed a microfluidic device to study the blood-brain barrier.
Genetic Links to Brain Cancer Cell Growth
Researchers discover clues to tumour behaviour from genetic differences between brain cancer cells and normal tissue cells.
Predicting Leukaemia Development in Cancer Patients
Biomarker may predict which formerly treated cancer patients will develop highly fatal form of leukemia.
Making Personalized Medicine a Reality
Groundbreaking technique developed at McMaster University is helping to pave the way for advances in personalized medicine.
Secret Phenotypes: Disease Devils in Invisible Details
Algorithmic deep phenotyping exposes masses of hidden traits and possible subtle genetic connections relevant to unseen influences on disease.
Hunting the Missing Link Between Genetics and the Environment
The International Phenome Centre Network (IPCN) works to transform healthcare through phenomics - the dynamic interactions between our genes and our environment.
Gene Limits Desire To Drink Alcohol
Research teams have identified a gene variant that suppresses the desire to drink alcohol.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!