Corporate Banner
Satellite Banner
Genotyping & Gene Expression
Scientific Community
Become a Member | Sign in
Home>News>This Article

Thermo Fisher, Cellectis Enter TAL Nucleases Licensing Agreement

Published: Thursday, June 05, 2014
Last Updated: Thursday, June 05, 2014
Bookmark and Share
Cellectis and Thermo Fisher Scientific announced that they have entered into a series of agreements covering the uses of TAL nucleases under the brand name TALEN™.

Pursuant to these agreements, Thermo Fisher is granted a worldwide license under Cellectis’ rights to the TAL nucleases outside the therapeutic field, with exclusive rights to grant sublicenses in research and development, bioproduction and certain applied markets. Thermo Fisher currently markets TALEN™ for these applications under its Life Technologies brand. 

Cellectis is granted a worldwide license under Thermo Fisher’s rights to TAL nucleases in the research and development field for internal and collaborative research, for commercialization of TAL gene editing for Cellectis bioresearch’s products and services, and in the plant biotechnology field for Cellectis plant sciences’ in-house and collaborative research and development. Finally, Cellectis is granted a worldwide license for therapeutic research and development, including rights to grant sublicenses for therapeutic uses in the fields of T cells and Natural Killer cells. 

Dr. André Choulika, Chairman and Chief Executive Officer of Cellectis stated: “We are very pleased to enter into these agreements that strengthen Cellectis’ position in the uses of TALEN™ gene editing in Cellectis’ core businesses, and solidifies our position as a leader in the field of engineered CART Chimeric Antigen Receptors therapeutics. TALEN™ is the state-ofthe- art for gene editing and provides exceptional precision, safety, efficacy and ease of use. TAL nucleases have many applications in genome engineering and their efficacy and specificity make them the world’s best gene editing technology for therapeutic applications. Cellectis founded the field of gene editing 14 years ago and is now primarily focused on adoptive immunotherapy using TALEN™-engineered T cells combined with (CARs).” 

“The agreements between Thermo Fisher and Cellectis create a powerful intellectual property portfolio comprised not only of the foundational work conducted at the University of Minnesota and Martin-Luther-Universitat Halle-Wittenberg, but also additional intellectual property controlled by each party,” said Helge Bastian, general manager and vice president of synthetic biology at Thermo Fisher Scientific. “The ability of TAL effectors to bind to DNA with unprecedented precision and reliability makes this technology invaluable to researchers looking to edit genomes and control gene activity. The current alliance clarifies the path for the use of TALEN™ gene editing in research and applied markets, and represents a major milestone in Thermo Fisher’s strategy to build a comprehensive gene editing technology platform.” 

Commercial terms of the agreements were not disclosed. 

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Transcriptome Profiling Grants Launched
Request for proposal aims to identify promising research projects involving precious samples.
Monday, October 20, 2014
Thermo Fisher Scientific, GSK and Pfizer Collaboration
Thermo Fisher Scientific announces agreement with GlaxoSmithKline and Pfizer to develop oncology companion diagnostics using Next-Generation Sequencing (NGS.)
Thursday, September 25, 2014
Thermo Fisher Scientific and Newman-Lakka Institute to Collaborate
The collaboration will research diagnostic approaches for personalized cancer treatment.
Tuesday, June 25, 2013
Scientific News
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Personalized Drug Screening for Multiple Myeloma Patients
A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
New Way to Force Stem Cells to Become Bone Cells
Potential therapies based on this discovery could help people heal bone injuries or set hardware, such as replacement knees and hips.
Promise of Newborn Stem Cells to Revolutionize Clinical Practice
In this article Shweta Sharma, PhD, discusses the potential of an Umbilical Cord Blood bank as an untapped source of samples for research and clinical trials.
New Anti-Malarial Drug Screening Model
University of South Florida researchers demonstrate novel chemogenomic profiling to identify drug targets for the most lethal strain of malaria.
Coronavirus Breakthrough
Protein mutation affects spread and virulence of respiratory virus.
New, Better Test for Prostate Cancer
A study from Karolinska Institutet shows that a new test for prostate cancer is better at detecting aggressive cancer than PSA.
Circadian Clock Controls Insulin and Blood Sugar in Pancreas
Map of thousands of genes suggests new therapeutic targets for diabetes.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos