Corporate Banner
Satellite Banner
Genotyping & Gene Expression
Scientific Community
Become a Member | Sign in
Home>News>This Article

Chinese University of Hong Kong Selects Fluidigm’s BioMark™ System for Molecular Diagnostic Applications

Published: Wednesday, May 23, 2007
Last Updated: Wednesday, May 23, 2007
Bookmark and Share
The University will use the system to detect and quantify viruses associated with cancer as well as for research on other molecular diagnostic applications.

Fluidigm has announced that the Department of Chemical Pathology, at The Chinese University of Hong Kong (CUHK), has adopted the BioMark Real-time PCR System. The system is based on BioMark dynamic arrays and digital arrays - nanofluidic chips for genetic analysis.

The laboratory, under the direction of Professor Dennis Lo, is using the system to detect and to quantify viruses associated with cancer, to detect somatic mutations in a high background of normal genes, and to develop gene expression profiles, as well as for research on other molecular diagnostic applications.

“We are delighted that this leading Chinese reference laboratory, in an emerging area of healthcare, will be validating our system as a clinical research tool,” said Fluidigm CEO Gajus Worthington.

The BioMark system has significant advantages in a clinical research setting over conventional microplates. Dynamic arrays are tailored for high-throughput multiplexed gene expression analyses, i.e., for the parallel testing of many samples against many genes. Thus, they are ideal for validating gene signatures across many patient samples.

An array generates 2,304 PCR reactions, requiring orders of magnitude less reagent and liquid transfer steps than conventional formats.

While dynamic arrays combine components to create PCR assays, digital arrays have an architecture that partitions a sample into more than 700 parts. If a rare mutation is present, it is isolated in a chamber and detectable by PCR, even if it is present in very low copy numbers.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Fluidigm, OpGen Collaborate
Fluidigm and OpGen have announced an agreement to collaborate on instruments and kits to test for multi-drug resistance genes in bacteria, fungi, and viruses.
Tuesday, July 14, 2015
Fluidigm to Acquire DVS Sciences
The acquisition consideration of approximately $207.5 million consists of a combination of Fluidigm common stock and cash.
Wednesday, January 29, 2014
Singapore Single-Cell Research Centre Opens Door for Asian Biological Discoveries
Centre dedicated to diagnosis and treatment derived from single-cell exploration.
Monday, April 29, 2013
Fluidigm Announces $60 Million Public Offering of Common Stock
Company has closed the previously announced underwritten public offering of 4,209,000 shares of its common stock at a price to the public of $14.25 per share for gross proceeds of approximately $60 million.
Wednesday, August 22, 2012
Leading Leukemia Lab Invests In Fluidigm Access Array™ and EP1™ Systems
Fluidigm Corporation has announced that MLL Munich Leukemia Laboratory ( has purchased Access Array™ and EP1™ Systems.
Tuesday, November 16, 2010
Cancer Research UK Purchases Fluidigm Genotyping System
The research centre will utilize high-throughput SNP genotyping to identify and verify genetic variants underlining susceptibility to various cancers.
Friday, June 05, 2009
Scientific News
Cell's Waste Disposal System Regulates Body Clock Proteins
New way to identify interacting proteins could identify potential drug targets.
Compound Doubles Up On Cancer Detection
Researchers have found that tagging a pair of markers found almost exclusively on a common brain cancer yields a cancer signal that is both more obvious and more specific to cancer.
Lung Repair and Regeneration Gene Discovered
New role for hedgehog gene offers better understanding of lung disease.
Mixed Up Cell Transportation Key Piece of ALS and Dementia Puzzle
Researchers from the University of Toronto are one step closer to solving this incredibly complex puzzle, offering hope for treatment.
Five New Genetic Variants Linked to Brain Cancer Identified
The biggest ever study of DNA from people with glioma – the most common form of brain cancer – has discovered five new genetic variants associated with the disease.
Predictive Model for Breast Cancer Progression
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
New Hope for Personalized Treatment of Eczema
Pharmaceutical researchers at Oregon State University have developed a new approach to treat eczema and other inflammatory skin disorders that would use individual tests and advanced science to create personalized treatments based on each person's lipid deficiencies.
Gene Expression: A Snapshot of Stem Cell Development
New genes found that regulate development of stem cells.
Are Changes to Current Colorectal Cancer Screening Guidelines Required?
Editorial suggests more research is needed to pinpoint age to end aggressive screening.
Assessing Cancer Patient Survival and Drug Sensitivity
RNA editing events another way to investigate biomarkers and therapy targets.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos