IPSOGEN Grants Labcorp License for Leukemia Molecular Diagnostic Assay in USA
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IPSOGEN has announced the signing of an agreement with Laboratory Corporation of America® Holdings under which LabCorp will offer a JAK2 molecular diagnostic assay in the USA.
According to the terms of the agreement, IPSOGEN grants LabCorp non-exclusive rights, for the US territory, to offer an assay for the molecular classification and the diagnosis of a group of leukemias caused by JAK2 gene variations.
Additional terms were not disclosed. The test is based on mutations in the JAK2 gene, to which IPSOGEN has worldwide exclusive intellectual property rights. A high proportion of patients with myeloproliferative disorders (MPD; polycythemia vera, essential thrombocythemia, idiopathic myelofibrosis) carry a dominant gain-offunction V617F mutation in the JH2 kinase-like domain of JAK2.
This pioneering work published in a 2005 issue of Nature by the INSERM team of Dr. Vainchenker (Institut Gustave Roussy, Paris) provides a breakthrough progress for the molecular classification and the diagnosis of myeloproliferative disorders. The license allows LabCorp to provide the JAK2 mutation assay through its various CLIA-registered laboratories throughout the USA.