|Does the increase of exosomal microRNAs reflect an activated immune system in melanoma?|
Nina Koliha, Florian S. Dreyer , Jochen Dindorf , Andreas Bosio, Andreas S. Baur , and Stefan Wild
Cutaneous malignant melanoma is a form of skin cancer that accounts for 65% of skin cancer-related deaths. The incidence increases continuously, and while early detection leads to nearly 100% survival rates, the mortality raises to greater than 80% for patients with advanced disease.
|A New Approach to Increase Yields and Improve Functionality of Recombinant Proteins|
Antti Vasala, BioSilta Oy, Oulu, Finland
The ability to express and extract fully functional proteins in sufficient quantities from bacterial cultures is a prerequisite for many projects in which recombinant proteins are required for structural studies, functional characterization, as assay components or for other applications. However, low yield, poor solubility and lack of functionality are often associated with, what should be, a routine procedure.
|Marking of Weighing Equipment for Hazardous Areas|
This poster outlines typical markings for hazardous areas.
|Over-representation of Proteins Identified as Disease Biomarkers and their Relation to Post-Mortem Events|
B. Orback, K. Kultima, M. Borén, M. Söderquist and K. Sköld
Tissue sampling is a major traumatic event that can have drastic effects within a very short timeframe at the molecular level resulting in loss of sample quality due to post sampling changes. It has recently been reported that the same proteins, regardless of
tissue origin or species, are often found expressed differentially in various disease states, bringing into question the significance of these proteins as biomarkers.
|Cloning And Purification of a Putative Repressor Protein from Arthrobacter nicotinovorans Pao1|
Marius Mihasan, Marius Stefan, Hritcu Lucian, Vlad Artenie
The soil bacterium Arthrobacter nicotinovorans carries the pAO1 catabolic megaplasmid which enables it to grow on nicotine (Igloi and Brandsch, 2003).
|Protein Microarrays for Characterisation of the Bacillus anthracis ‘infectome’|
Stephen Kidd, Karen Kempsell, Rebecca Ingram, Pierre Watteau, Daniel Altmann, Michael Elmore, Sue Charlton, Bassam Hallis and Richard Vipond
These studies provide an interesting insight into the transcriptome of virulent B. anthracis in a host infection environment.
|Kidney Genes Expression in Hypertensive ISIAH Rats|
The present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.
|Variation in miRNA expression between TRV-infected tobacco plants is correlated with symptom severity and TRV-16K transcripts abundance|
Zhimin Yin, Krystyna Michalak, Miroslawa Chrzanowska
In the present work, expression of certain miRNAs and their targets were investigated in three tobacco plants infected with Tobacco rattle virus (TRV) isolate Deb57 collected from Northern Poland in 2008.
|Application of the SoftFocus® Design Strategy to Epigenetics Targets|
Sheppard D, Macritchie J, Allen V & Hughes S
Epigenetics describes the regulation of gene expression that occurs through DNA methylation and post translational modification of histones. The pharmaceutical industry has shown an explosion of interest in this field with new targets emerging.
|Improved Ligation Specificity with Chemically Modified Ligation Components|
Sabrina Shore, Alexandre Lebedev, Elena Hidalgo Ashrafi, Gerald Zon, Natasha Paul, Richard Hogrefe
Ligases are gaining utility in molecular biology applications, such as nucleotide sequence detection, single nucleotide polymorphism (SNP) detection, protein detection and “next generation” sequencing by ligation.
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