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A New Approach to Increase Yields and Improve Functionality of Recombinant Proteins
Antti Vasala, BioSilta Oy, Oulu, Finland

The ability to express and extract fully functional proteins in sufficient quantities from bacterial cultures is a prerequisite for many projects in which recombinant proteins are required for structural studies, functional characterization, as assay components or for other applications. However, low yield, poor solubility and lack of functionality are often associated with, what should be, a routine procedure.

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Marking of Weighing Equipment for Hazardous Areas

This poster outlines typical markings for hazardous areas.

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Over-representation of Proteins Identified as Disease Biomarkers and their Relation to Post-Mortem Events
B. Orback, K. Kultima, M. Borén, M. Söderquist and K. Sköld

Tissue sampling is a major traumatic event that can have drastic effects within a very short timeframe at the molecular level resulting in loss of sample quality due to post sampling changes. It has recently been reported that the same proteins, regardless of tissue origin or species, are often found expressed differentially in various disease states, bringing into question the significance of these proteins as biomarkers.

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Cloning And Purification of a Putative Repressor Protein from Arthrobacter nicotinovorans Pao1
Marius Mihasan, Marius Stefan, Hritcu Lucian, Vlad Artenie

The soil bacterium Arthrobacter nicotinovorans carries the pAO1 catabolic megaplasmid which enables it to grow on nicotine (Igloi and Brandsch, 2003).

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Integrating compound storage into automated laboratory workflows
James Craven, Simon Tullett

This poster discusses the benefits of comPOUND for automated sample storage and delivery. TTP Labtech’s pneumatic transport technology, lab2lab, integrates these stores with other instrumentation into managed, fully automated workflows, allowing the scientist to focus on research and data analysis.

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A mix-and-read cell-based assay for antibody screening against Epithelial Growth Factor Receptor
Wayne P Bowen, David Onley, Paul Wylie, Diana Caracino and Tristan Cope

Here we present a sensitive robust, mix-and-read method for the screening of antibodies against cell surface proteins. With its simple operation, no-wash format, and high sensitivity, this new method is well-suited for high throughput antibody screening.

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Protein Microarrays for Characterisation of the Bacillus anthracis ‘infectome’
Stephen Kidd, Karen Kempsell, Rebecca Ingram, Pierre Watteau, Daniel Altmann, Michael Elmore, Sue Charlton, Bassam Hallis and Richard Vipond

These studies provide an interesting insight into the transcriptome of virulent B. anthracis in a host infection environment.

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Low cost, low footprint, expandable automated biobanking solutions
James Craven, Chris Morris, Maud Godfrey, Danielle Miller

This case study describes how TTP Labtech’s comPOUND storage modules have been employed by Abcam, a worldwide supplier of antibodies. Here, the turnaround time of sample placement and retrieval is an essential component for high quality service to its customers.

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Kidney Genes Expression in Hypertensive ISIAH Rats
Tatyana Pylnik

The present study was performed to detect the key genes involved in the hypertensive phenotype manifestation in the ISIAH rats with inherited stress-induced arterial hypertension.

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Showing Results 61 - 70 of 172
Scientific News
Genetically Speaking, Mammals Are More Like Their Fathers
A first of its kind study shows that who we inherit genetic variants from – our mother or father – is crucial for the development of diseases and for research studies aimed at finding causes and potential treatments.
A Faster, Less Expensive Way To Analyze Gene Activity
Yale researchers have devised a method that could reduce the time and cost of analyzing gene activity.
Epigenomics of Alzheimer’s Disease Progression
Study of epigenomic modifications reveals immune basis of Alzheimer's disease.
Single-Cell, 42-plexed Protein Analysis Achieved with a New Microchip Technology
A novel microdevice capable of detecting 42 unique immune effector proteins has been developed.
New Therapeutic Strategy Discovered for Ovarian Cancer
New therapeutic target could lead to the first effected targeted therapy for aggressive forms of ovarian cancer.
MAGE Genes Provide Insight into Optimizing Chemotherapy
UT Southwestern Medical Center scientists have identified a new biomarker that could help identify patients who are more likely to respond to certain chemotherapies.
Dynamic Profiling Of The Protein Life Cycle In Response To Pathogens
A quantitative genomic model is used to explain the abundance of proteins in cells based on mRNA expression, translation, and degradation.
New Biomarkers To Spot Pancreatic Cancer Early
A combination of two biomarkers can identify pre-clinical pancreatic cancer.
Two Genetic Mutations That Interact To Lower Heart Attack Risk Identified
About 20 percent of the population has this protective genetic combination.
Epigenetic Signatures that Differentiate Triple-Negative Breast Cancers
Australian researchers have identified epigenetic ‘signatures’ that could help clinicians tell the difference between highly aggressive and more benign forms of triple-negative breast cancer.
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