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Biomarker Discovery Strategy for Trisomy 21 Using iTRAQ and 4800 Plus MALDI TOF/TOF


Plasma proteins serve as good indicators of disease as there are representative proteins from several cellular processes and thus a potential source for biomarker discovery. The large dynamic range of plasma proteins makes the analysis very challenging, as a large number of low abundance proteins are masked by a few high abundance proteins.

Date Posted: 25/09/2007 10:28:14

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