NIH Common Fund Researchers Uncover Structure of Important Target for Drug DesignResearchers have uncovered a potent class of small molecules that selectively turn on the S1P1 receptor.
New Findings in Drug-Induced Receptor ActivityThe discovery that drugs targeting a single GPCR can differentially modulate distinct subsets of the receptor signaling repertoire is a very important step in drug discovery.
A Modified MS2 Bacteriophage Plaque Reduction Assay for the Rapid Screening of Antiviral Plant ExtractsThe ability of the MS2 plaque reduction assay to detect antiviral activity in these known antiviral plant preparations indicates its suitability as an antiviral screening tool.
Cyclofluidic Announces First Fully Automated Lead Discovery ExperimentScientists used the company’s proprietary microfluidic system to design, make and screen potential drug molecules active against thrombin, a target associated with stroke.
Hamilton Introduces Automated DNA Sample Enrichment SolutionSystem uses Roche 454 REM e liquid handling system to replace hours of manual work.
Dundee Researchers Seek to Beat "Molecular Obesity"Researchers from the University of Dundee have come up with a new innovative approach in the quest to reduce failure rates in the drug discovery process.
OGT Releases New Whitepaper for Aiding Biomarker DiscoveryThe new document explores the need for biomarkers as indicators of disease, and discusses the vast potential of autoantibodies as markers of early disease development.
Scripps Research Scientists Create Novel RNA Repair TechnologyDiscovery could aid search for Huntington’s, Spinocerebellar Ataxia, and Kennedy Disease treatments.
Scientists Uncover Novel Mechanism of Glioblastoma DevelopmentResearchers believe understanding molecular mechanisms can lead to new treatments. Work focuses on importance of post-transcriptional regulation.
Ganetespib Synergizes with Taxanes in Multiple Non-small Cell Lung Cancer ModelsCombination of ganetespib with microtubule stabilizers, docetaxel and paclitaxel, or destabilizers, vincristine, was shown to result in synergistic anticancer activity.
