Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>Events>This Event
  Events - September 2014


SLAS Short Courses

01 Sep 2014 - 01 Sep 2014 - Manchester, UK



Bookmark and Share


The courses are complementary to the conference program; their objective is to educate people interested in these fields, providing an in-depth understanding of the topic and a comprehensive overview of the key techniques and recent developments. Delivered by distinguished faculty, these courses address a range of timely issues using real-world examples.

Later, in the conference, you can hear from researchers actively involved in these areas about their experiences and how the leading-edge is being explored !

The quality and educational content of SLAS short courses is well recognized and very well respected in our industry, and we are pleased to be partnering with SLAS to deliver these to you.

There is a charge to attend the short-courses, whilst the main Drug Discovery conference on Tue 2nd and Wed 3rd Sept remains free to attend ( please register for each separately ).

COURSE 1 : Introduction to Laboratory Automation

Jonathan Wingfield : AstraZeneca
Malcolm Crook : Peak Analysis & Automation

This introduction to automation course will provide a basic overview of when and how to successfully deploy automation within a laboratory environment. The course is tailored for managers who want to understand the strategic and tactical options for automation deployment. There will be an overview of the principles of automation architecture, infrastructure and laboratory informatics. There is no requirement for a working knowledge of, or experience with, automation.

View / download a full course summary.

COURSE 2 : High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis

Eberhard Krauß : ChemBioCon
Marc Bickle : Head HT-Technology Development Studio, Max Planck Institute of Molecular Cell Biology and Genetics

High-content screening is a powerful technology platform for implementing functional cell-based assays that allow truly multi-parametric analysis in the physiological context of intact cells. This course provides a state-of-the-art overview of the components of HCS (instrumentation, reagents, HC assay development, automated image analysis and multi-parametric data analysis, and data standards) together with some showcases of small molecule and RNAi high-content screens in industry and academia.

A demonstration will be given using the open source software CellProfiler how to analyze early endosomes in HeLa cells. Nuclei, cytosol and endosomes will be segmented and quantified. The resulting data will then be analyzed using the open source software KNIME. Parameters will be tested for normality, normalized and assembled into multiparametric profiles. The profiles will be quantified to estimate phenotypic strength and clustered to determine phenotypes. Both the slides describing the analysis and the pipelines will be made available to course participants to allow them to recreate the workflow in their own laboratories.

View / download a full course summary.

COURSE 3 : Establishing Cell-Based Assays and Implementing 3D Culture Models for screening and drug testing

Terry Riss : Senior Product Specialist, Cell Health, Promega Corporation
Jens Kelm : Insphero

This course will describe developing standard procedures for handling cultured cells to set up cell-based assays, describe techniques for measuring cell health and the mechanisms leading to cytotoxicity, and provide an overview of recent technological advances in 3D culture technologies that enable automation-compatible drug testing with more predictive and biologically relevant assays. Case studies will be presented which provide examples of using 3D model systems for screening and drug testing.

View / download a full course summary.



Further information
Scientific News
Promising Class of New Cancer Drugs Cause Memory Loss in Mice
New findings from The Rockefeller University suggest that the original version of BET inhibitors causes molecular changes in mouse neurons, and can lead to memory loss in mice that receive it.
Electrical Control of Cancer Cells
Research led by scientists at The University of Texas Health Science Center at Houston (UTHealth) has revealed a new electrical mechanism that can control these switches.
Signature of Microbiomes Linked to Schizophrenia
Studying microbiomes in throat may help identify causes and treatments of brain disorder.
Inflammation Linked to Colon Cancer Metastasis
A new Arizona State University research study led by Biodesign Institute executive director Raymond DuBois has identified for the first time the details of how inflammation triggers colon cancer cells to spread to other organs, or metastasize.
Structural Discoveries Could Aid in Better Drug Design
Scientists have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output.
Determining the Age of Fingerprints
Watch the imprint of a tire track in soft mud, and it will slowly blur, the ridges of the pattern gradually flowing into the valleys. Researchers have tested the theory that a similar effect could be used to give forensic scientists a way to date fingerprints.
Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies
CHOP genomics expert leads analysis of genetic architecture, with eye on repurposing existing drugs.
Surprising Mechanism Behind Antibiotic-Resistant Bacteria Uncovered
Now, scientists at TSRI have discovered that the important human pathogen Staphylococcus aureus, develops resistance to this drug by “switching on” a previously uncharacterized set of genes.
Tissue Bank Pays Dividends for Brain Cancer Research
Checking what’s in the bank – the Brisbane Breast Bank, that is – has paid dividends for UQ cancer researchers.
Researchers Publish Landmark “Basket Study”
Researchers from Memorial Sloan Kettering Cancer Center (MSK) have announced results from the first published basket study, a new form of clinical trial design that explores responses to drugs based on the specific mutations in patients’ tumors rather than where their cancer originated.
Scroll Up
Scroll Down
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!