The application poster details the use of a MicroFlo™ Select Dispenser, Precision™ Automated Microplate Pipetting System and Synergy™ 4 Multi-Mode Microplate Reader with a novel 3-D cell culture method and FRET-based assay to measure activity of a Histamine H1 G protein-coupled Receptor.
This collaboration is an opportunity to explore new paradigms for cell-based assay workflows and microplate-based screening of 3-D cell cultures. “Customers are using BioTek’s plate readers for cell-based assays to an increasing extent,” explains Peter Banks, Scientific Director at BioTek Instruments. “We are particularly interested in collaborating with companies that provide novel enabling technologies such as the BioLevitator and GEM technologies for improving cell-based assay workflows. Being able to dispense cells directly into the assay without enzymatic detachment offers a unique workflow advantage and potential benefits to cell health and assay performance.” Future studies will include primary cell lines as well as kinase screening, ADME/Tox and live cell assays.