Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

DiscoveRx Corporation Continues to Innovate with Solutions for Epigenetic Drug Discovery Programs

Published: Monday, February 06, 2012
Last Updated: Monday, February 06, 2012
Bookmark and Share
The company announced availability of platform for studying Bromodomains, an emerging class of epigenetic targets.

The new platform designated as BROMOscan(TM), is based on the proven KINOMEscan(TM) technology and will enable high throughput screening, selectivity profiling and quantitative Kd determinations across several sub-families of bromodomains, including the BET family.

The platform enables screening for selective inhibitors of Bromodomain epigenetic "reader" proteins that bind and recognize acetylated lysine residues on histone tails, which are important epigenetic marks associated with gene expression and regulation. With many drug discovery programs aimed at identifying small molecules that inhibit Bromodomains, the availability of a quantitative and high-throughput platform represents a substantial leap forward and a powerful solution to support new discovery programs while supporting and expediting existing projects.

"With the recent understanding that epigenetics plays a pivotal role in inflammation and oncology, now more than ever the drug discovery community is seeking an enabling platform for high throughput screening of epigenetic targets," said Dr. Pyare Khanna, President & CEO of DiscoveRx. "Our goal was to leverage our in-house expertise platforms to build a high quality, first in class panel of Bromodomain ligand binding assays."

With over 25% coverage of the human bromodomain targets anticipated in the first panel, DiscoveRx extends its leadership position by offering screening and profiling solutions for key drug targets such as GPCRs, Kinases, NHRs and now epigenetic targets. This milestone achievement reaffirms DiscoveRx's continued commitment to invest in developing innovative products and solutions for the drug discovery community.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Validation of Drug Toxicity Prediction using DiscoveRx Model
BioMAP® Systems was shown to identify important safety aspects of drugs and chemicals more efficiently and accurately than can be achieved by animal testing.
Tuesday, May 20, 2014
DiscoveRx Expands its GPCR Technology Portfolio to Include Advanced Technologies
Introduces two additional GPCR platforms to facilitate counterscreening, lead optimization and SAR evaluation of compounds.
Friday, April 09, 2010
Scientific News
New Biomarker to Assess Stem Cells Developed
A research team led by scientists from UCL have found a way to assess the viability of 'manufactured' stem cells known as induced pluripotent stem cells (iPSCs). The team's discovery offers a new way to fast-track screening methods used in stem cell research.
A Better Model for Parkinson's
Scientists at EPFL solve a longstanding problem with modeling Parkinson’s disease in animals. Using newfound insights, they improve both cell and animal models for the disease, which can propel research and drug development.
Faster Drug Discovery?
Startup develops more cost-effective test for assessing how cells respond to chemicals.
Microalgae Make a Splash in the UK Cosmeceutical Market
Scottish innovators have discovered an anti-viral and anti-inflammatory carbohydrate in microscopic algae (microalgae) which has huge potential to change the cosmetics market.
Mechanism of Tumor Suppressing Gene Uncovered
The most commonly mutated gene in cancer,p53, works to prevent tumor formation by keeping mobile elements in check that otherwise lead to genomic instability, UT Southwestern Medical Center researchers have found.
Experimental Combination Surprises with Anti-HIV Effectiveness
A compound developed to protect the nervous system from HIV surprised researchers by augmenting the effectiveness of an investigational antiretroviral drug beyond anything expected.
Useful Colon Cancer Biomarker Discovered
Biomarker is detectable with simple, inexpensive test.
A New Type of Anticancer Agent
Success in the development of a ?-tubulin specific inhibitor.
Seeing Hope
Gene therapy/drug combo restores some vision in mice with optic nerve injury.
Versatile New Molecule-Building Technique
Chemists at The Scripps Research Institute (TSRI) have devised a new and widely applicable technique for building potential drug molecules and other organic compounds.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!