Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

MRC Technology Launches Small Molecule Compound Library Access Scheme

Published: Thursday, September 20, 2012
Last Updated: Thursday, September 20, 2012
Bookmark and Share
Subset of compound library to be made available to academic researchers free of charge.

MRC Technology has announced the launch of a scheme under which it will provide access to a representative subset of 9,000 compounds from its 150,000 small molecule compound library to academic research institutes free of charge.

The scheme has been launched by MRC Technology to provide academics with a high quality compound library for screening, to reduce academic spend on libraries less suited to screening, and to encourage groups to tap into MRC Technology’s drug discovery expertise for research programmes.

Under the terms of the scheme, participating academics will receive the 9,000 compounds in plate format and in return MRC Technology will have first refusal on collaboration agreements for any drug development programmes resulting from screens of the compound library.

Assay data will be jointly owned by MRC Technology and the research institute, giving MRC Technology a better understanding of how its library is performing against a diverse range of targets and enabling further enhancement of the library through an iterative process.

MRC Technology’s compound library has been built and curated by its medicinal chemistry and computational chemistry scientists.

The library includes 100,000 high quality, diverse, drug-like compounds with hit-like properties, with an additional 50,000 compounds in subsets targeted to specific protein classes.

The 9,000 compounds available through the scheme have been chosen to represent a cross-section of the full library.

Institutes joining the scheme will also benefit from access to advice on suitable assay design and screening formats, and optimization of screening hits, from MRC Technology’s team of scientists.

“We have seen an increase in assay throughput within academic research institutes, due to the availability of affordable small-scale robotics,” said Justin Bryans, Director of Drug Discovery at MRC Technology.

Bryans continued, “By offering access to our compound library with no fees attached, our aim is to stimulate drug discovery within the academic field by enabling these laboratories to carry out high quality, medium throughput screens and to potentially further develop any hits in collaboration with MRCT.”


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

MRC Technology Launches Respiratory ‘Call for Targets’
Project focused on potential small molecule or antibody targets in pathways important in the development or progression of respiratory disease.
Monday, March 02, 2015
Charities Pledge to Inject Millions to Jump Start Drug Development for Brain Diseases
MRC Technology to lead Neurodegeneration Medicines Acceleration Programme to uncover promising drugs in pharma libraries.
Tuesday, November 18, 2014
MRC Technology Negotiates License with Bio-Techne for MRC’s GOPAL Protein Synthesis Technology
Technology enables production of ubiquitin reagents and other proteins for use in drug discovery.
Wednesday, August 27, 2014
MRC Technology, AstraZeneca Renew Target Discovery Collaboration
Initiative brings together global expertise to share compound libraries and streamline drug discovery.
Thursday, July 03, 2014
MRC Technology Sells its MCRs Programme to Pfizer
Small molecules developed in collaboration with Queen Mary University of London.
Thursday, June 19, 2014
MRC Technology, Daiichi Sankyo form Drug Discovery Collaboration
Initiative brings together global expertise to streamline drug discovery.
Wednesday, May 14, 2014
£3m Dementia Consortium Launched
New Consortium aims to boost dementia drug discovery by uniting charity, academic and private sectors in search for new treatments.
Wednesday, December 11, 2013
MRC Technology and Oxford University Collaborate
The project will screen TRESK potassium channel activators involved in migraine pain control.
Thursday, November 14, 2013
MRC Technology and Renishaw Diagnostics Collaborate
Initiative combines expertise to accelerate clinical diagnostic screening.
Thursday, October 03, 2013
MRC Technology Forms Alliance with World Leading Translational Research Centres
The aim of this alliance is to strengthen the international academic and/or not-for-profit drug development and commercialization network.
Monday, January 21, 2013
Scientific News
New Tool Uses 'Drug Spillover' to Match Cancer Patients with Treatments
Researchers have developed a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker (KAR) predicts what genetics are truly driving the cancer in any population of cells and chooses the best "kinase inhibitor" to silence these dangerous genetic causes of disease.
HIV Susceptibility Linked to Little-Understood Immune Cell Class
High levels of diversity among immune cells called natural killer cells may strongly predispose people to infection by HIV, and may be driven by prior viral exposures, according to a new study.
Sweet Revenge Against Superbugs
A special type of synthetic sugar could be the latest weapon in the fight against superbugs.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
Tracking Breast Cancer Before it Grows
A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes.
Zebrafish Reveal Drugs that may Improve Bone Marrow Transplant
Compounds boost stem cell engraftment; could allow more matches for patients with cancer and blood diseases.
DNA Damage Seen in Patients Undergoing CT Scanning
Along with the burgeoning use of advanced medical imaging tests over the past decade have come rising public health concerns about possible links between low-dose radiation and cancer.
The Light of Fireflies for Medical Diagnostics
EPFL scientists have exploited the light of fireflies in a new method that detects biological molecules without the need for complex devices and high costs.
Vital Protein in Healthy Fertilization Process Identified
Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!