Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

AB SCIEX and Phytronix Improve High-Throughput Pharmaceutical Application

Published: Thursday, October 18, 2012
Last Updated: Thursday, October 18, 2012
Bookmark and Share
Integration of LDTD with DiscoveryQuant software streamlines high-throughput method development.

AB SCIEX and Phytronix Technologies have announced the integration of Phytronix’s LDTD (Laser Diode Thermal Desorption) ion source with AB SCIEX’s DiscoveryQuant™ Software, giving discovery pharmaceutical scientists a faster, more streamlined method development process than was previously available for early ADME workflows.

The new solution was launched this week at the AAPS 2012 conference. It includes automated method optimization and is ideally suited for laboratories that run thousands of samples per day in a regulated environment, especially those with the need for global connectivity to compound database libraries.

The integration gives scientists the ability to use DiscoveryQuant Software to control the LDTD source and, when coupled with the AB SCIEX Triple Quad™ and QTRAP® mass spectrometry portfolio, to achieve speeds that rival any other product for high-throughput applications in the market today, with sample-to-sample cycle times as low as four seconds.

This MS/MS solution bypasses LC time scales, providing a much faster approach to method development and optimization. It is expected to improve efficiency and boost productivity.

“We are delivering on the promise of our initial collaboration announcement with AB SCIEX one year ago,” said Jean Lacoursiere, President of Phytronix Technologies. “We are delivering a more comprehensive and truly unmatched tool for drug discovery. We are proving that LDTD-MS/MS is a winning combination.”

By combining the LDTD source with DiscoveryQuant software, it is possible to automatically determine optimal ion path parameters for maximum sensitivity, while populating a shared central database with this critical information.

DiscoveryQuant can then access this method database for use in assays with the LDTD source. The output of this new LDTD-MS/MS workflow feeds into compound database libraries that pharmaceutical scientists need to advance their drug discovery and development work, and allows researchers worldwide to share MS/MS methodologies online.

“Working with innovative front-end source providers such as Phytronix is part of AB SCIEX’s commitment to the high-throughput market,” said Dave Hicks, Vice President of the Pharmaceutical and Academic Business at AB SCIEX.

Hicks continued, “With our expertise in software for MS/MS applications, we have extended our partnership with Phytronix to give pharmaceutical scientists access to a novel workflow that pushes the limits.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

SCIEX, University of Manchester Partner
SWATH® Acquisition-based next-generation proteomics technology promises to make industrial proteomics a reality.
Thursday, October 29, 2015
AB SCIEX Wins New Product Innovation Award in Asia Pacific
The award recognizes the company’s continued innovation in the mass spectrometry industry and a number of new products introduced into the market in recent years.
Thursday, October 30, 2014
Scientific News
Charting Kidney Cancer Metabolism
Changes in cell metabolism are increasingly recognized as an important way tumors develop and progress, yet these changes are hard to measure and interpret. A new tool designed by MSK scientists allows users to identify metabolic changes in kidney cancer tumors that may one day be targets for therapy.
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Honey’s Potential to Save Lives
The healing powers of honey have been known for thousands of years.
3-D Printed Lifelike Liver Tissue for Drug Screening
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling.
Cytoskeleton Crew
Findings confirm sugar's role in helping cancers survive by changing cellular architecture.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Valvena, GSK Sign New R&D Collaboration
Valneva to supply process development services for EB66® -based Influenza vaccines.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!