Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Leading Tuberculosis Experts Explore Shortcomings in Current Immigrant TB Screening Policy

Published: Tuesday, December 04, 2012
Last Updated: Tuesday, December 04, 2012
Bookmark and Share
Improved immigration policy and replacement of century-old diagnostic tests have potential to significantly reduce cases of latent tuberculosis in the UK.

Leading scientists and experts in the field of tuberculosis (TB) are meeting today to discuss how to improve national prevention strategies for the control of TB. UK is one of few countries in Western Europe which has seen an increase in the number of active TB cases in recent years. The group, chaired by Professor Peter Davies, Consultant Chest Physician at Liverpool Heart and Chest Hospital and Dr Onn Min Kon, Consultant Respiratory Physician at St Mary’s Hospital, is expected to acknowledge recent findings that current UK immigrant screening procedures miss more than 70 per cent of latent TB infection and develop a consensus on how replacing current diagnostic tools with new cutting-edge technology, can reduce disease burden and cost.

TB remains one of the most contagious and prevalent diseases in the world, with approximately nine million active cases globally. It is estimated that there are also about two billion people around the world infected with latent, or inactive, TB. Research shows that in people with latent TB, preventative treatment can reduce the risk of developing active TB by as much as 90 per cent – demonstrating the importance of identifying and treating latent disease.

In Britain, cases of TB increased by almost 50 per cent between 1989 and 2009, with 9,040 cases reported in the UK in 2009; in 2011, TB reached its highest peak in 30 years. Foreign-born individuals account for nearly three quarters of the country’s TB cases.

“A significant proportion of active TB cases in the UK stem from immigrants carrying latent TB, whose infections are ‘reactivated’ at some point after they arrive in this country” said meeting co-chair Professor Peter Davies, Consultant Chest Physician at Liverpool Heart and Chest Hospital. “Compounding this is that the diagnostic test that has traditionally been used for identifying latent TB infection is more than 100 years old, and is often inaccurate. Clearly, this is a two-pronged problem that requires a two-pronged solution – we need clearer strategies for testing for latent disease among immigrants, and better diagnostic tests to enable us to do so.”

The tuberculin skin test (TST), the tool traditionally used to identify latent TB infection, is the oldest diagnostic test in medical practice, and is widely acknowledged to have shortcomings in relation to specificity and is more difficult to administer in practice. To combat the lack of an acceptable test for latent TB, new, highly-specific and faster tests have been developed, known as interferon-gamma release assays (IGRAs). Already widely used in US, Europe and Asia, IGRAs have demonstrated significant value in both accurate diagnosis of the disease and cost-effectiveness of the tests, and data show that this cost-effectiveness would be replicated should IGRAs be used in the UK.

“We urgently need to stem the tide of rising TB cases in the UK,” said meeting co-chair Dr Onn Min Kon, Consultant Respiratory Physician at St Mary’s Hospital. “This is not a problem that can be tackled by healthcare professionals alone – it needs to be a joint effort with policy and society. We look forward to an informative discussion about how best to tackle the influx of TB infection stemming from the immigrant community, and how to incorporate the new, and much more efficient and effective, IGRA testing into our efforts to screen for and prevent the spread of TB.”

QIAGEN is sponsoring this symposium as part of their ongoing commitment to the field of TB.

QIAGEN markets the QuantiFERON-TB Gold, the leading test for detection of latent TB, which has worldwide approvals and is recommended in several national and international guidelines.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Hitachi High-Technologies, QIAGEN Collaborate
Hitachi High-Technologies Corporation and QIAGEN N.V. have entered into a long-term strategic collaboration involving initiatives to deliver important advances in molecular testing.
Thursday, June 18, 2015
QIAGEN Signs Ninth Master Collaboration Agreement for Companion Diagnostics
Master collaboration agreement is a framework for developing and commercializing QIAGEN companion diagnostics, paired with new or existing products.
Thursday, November 13, 2014
QIAGEN Licenses Blood Cancer Biomarkers
Exclusive global license from University of Tokyo enables development of QIAGEN assays for SF3B1 mutations, including NGS gene panels, for blood cancers.
Saturday, July 26, 2014
QIAGEN, Lilly form CDx Collaboration
Companies to co-develop companion diagnostics for simultaneous analysis of DNA and RNA biomarkers in common cancers.
Friday, May 30, 2014
FDA Approve QIAGEN PCR Kit For Use With Second Colorectal Cancer Drug
Clinically proven companion diagnostic gains U.S. approval to guide use of Amgen’s Vectibix® (panitumumab) in treatment of metastatic colorectal cancer.
Tuesday, May 27, 2014
QIAGEN Licences Biomarker for Blood Disorder from CeMM Vienna
Company plans to develop a molecular diagnostic test for the calreticulin mutations.
Thursday, April 10, 2014
QIAGEN Partners with Exosome Diagnostics
Molecular testing of biofluids promises unprecedented access to gene mutations, gene expression signatures and expression levels without costly, invasive tissue biopsies.
Wednesday, July 24, 2013
QIAGEN Expands Pipeline of Promising New Biomarkers for Development of Companion Diagnostics
Several lymphoma-related biomarkers, including EZH2 Y641 gene mutations, rights acquired from British Columbia Cancer Agency.
Monday, June 10, 2013
QIAGEN and Cardinal Health Collaborate to Offer Molecular Diagnostic Products to Smaller and Mid-Sized U.S. Hospitals
Collaboration creates distribution channel to previously underserved market segment.
Tuesday, May 01, 2012
QIAGEN to Supply Molecular Screening Solutions to Increase Safety of Blood Donations in Brazil
The supply agreement covers molecular sample and assay technologies for a national PCR-based blood screening program for HIV and HCV.
Friday, June 05, 2009
QIAGEN to Supply Molecular Screening Solutions to Increase Safety of Blood Donations in Brazil
The agreement to supply molecular sample and assay technologies for a PCR-based blood screening program for HIV HCV in Brazil.
Friday, May 29, 2009
QIAGEN Tests Clinically Verified for the Monitoring of Swine Flu
German Bernhard Nocht Institute and Spanish Reference Laboratory detect infections with the H1N1 strain using QIAGEN’s artus influenza test.
Monday, May 04, 2009
QIAGEN and CNCI to Establish Cervical Cancer Screening Program in Kolkata
The initiative will be conducted over 5 years and is expected to reach 50,000 women.
Monday, April 27, 2009
EU Launches Project to Improve In-Vitro Diagnostics
QIAGEN led-consortium to develop standards for patient sample processing in order to facilitate the discovery and prediction of diseases.
Tuesday, January 13, 2009
Nobel Prize to HPV Researcher Highlights Importance of Cervical Cancer Screening and Prevention
The Nobel Prize-winning discovery of the causal link between human papillomavirus (HPV) and cervical cancer has spurred lifesaving prevention technologies – such as HPV testing and HPV vaccines - that are helping to eradicate cervical cancer globally.
Tuesday, October 07, 2008
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
Tracking Breast Cancer Before it Grows
A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes.
Zebrafish Reveal Drugs that may Improve Bone Marrow Transplant
Compounds boost stem cell engraftment; could allow more matches for patients with cancer and blood diseases.
DNA Damage Seen in Patients Undergoing CT Scanning
Along with the burgeoning use of advanced medical imaging tests over the past decade have come rising public health concerns about possible links between low-dose radiation and cancer.
The Light of Fireflies for Medical Diagnostics
EPFL scientists have exploited the light of fireflies in a new method that detects biological molecules without the need for complex devices and high costs.
Vital Protein in Healthy Fertilization Process Identified
Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice.
Teeth Reveal Lifetime Exposures to Metals, Toxins
Researchers have identified dental biomarkers to reveal links between early iron exposure and late life brain diseases.
Simple Technology Makes CRISPR Gene Editing Cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA.
Could a simple saliva test detect Alzheimer's?
Researchers have presented findings suggesting that a simple, non-invasive diagnostic for Alzheimer's could be within reach.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!