Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

CYTOO’s 2D+ Technology and Institut Curie’s Organelle Map in the limelight at SLAS 2013

Published: Monday, January 07, 2013
Last Updated: Monday, January 07, 2013
Bookmark and Share
CYTOO will attend the Society for Laboratory Automation and Screening (SLAS) 2013 conference on 12-16 Jan, in Orlando, Florida, USA.

The company will present their 2D+ Solutions, opening fresh perspectives for cell based assay development in drug discovery.

2D+ Solutions are based on CYTOO’s standard and custom adhesive micropatterns in 96-well plates which guide cell architecture and behavior. By defining the 2D topology of cell adhesion, the 2D+ Cell Culture Platform enables fine control of the spreading and 3D shape of cultured cells in single- or multi-cellular configurations. This approach results in control of cell contractility, cell polarity, organelle positioning, and cell division axis.

2D+ Custom Solutions are specifically designed to bring expertise, resources and technology to address current bottlenecks in cell based assay development and screening in drug discovery.

2D+ Custom Solutions include: Exploratory solutions to guide customers through the initial exploration of the 2D+ technology with experienced PhD-level expert support; Assay development to select the best ecosystem for the requested cells; Screening to run pilot or full sized screens. All Solutions are tailored to the customer’s needs and can be carried out in the customer’s facilities or outsourced to CYTOO, on our fully equipped HCS screening platform.

The 2D+ technology addresses a major concern with traditional 2D culture, in which cells spread and move in an uncontrolled manner, introducing a considerable but unnoticed variability in cell function. Kristine Schauer, from the Institut Curie in Paris, France, used the crossbow adhesive micropatterns to get reproducible shape and distribution of intracellular compartments and developed a mathematical algorithm to generate and compare probabilistic density maps of the different endosome compartments.

This innovative approach is a powerful universal method to identify statistically relevant hits and drug effects in complex cell based assays, and according to Michel Bornens, COO at CYTOO “the method has now the potential to become a gold-standard in the quantitative analysis of cell-based high-throughput data”. Kristine Schauer’s Organelle Map figures among the nine 2013 SLAS Innovation Award finalists. A $10,000 cash prize will be attributed during SLAS 2013, and recognizes extraordinary achievement in innovative laboratory science and technology.

Attendees are invited to visit booth #310 to discuss their application with François Chatelain, President and CEO, and Lisa Minor, Application Development Leader.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
It’s Now Easier To Go With The Flow
Rice University tool simplifies comparison of flow cytometry data for laboratories.
FNIH Launches Project to Evaluate Biomarkers in Cancer Patients
Company has announced that it has launched a new project to evaluate the effectiveness of liquid biopsies as biomarkers in colorectal cancer patients.
Drugs that May Combat Deadly Antibiotic-Resistant Bacteria Uncovered
Study identifies 79 compounds that inhibit carbapenem-resistant Enterobacteriaceae (CRE).
Making Precision Medicine a Reality
Researchers are one step closer to understanding the genetic and biological basis of diseases like cancer, diabetes, Alzheimer’s and rheumatoid arthritis – and identifying new drug targets and therapies.
Potential “Good Fat” Biomarker
New method to measure the activity of energy consuming brown fat cells could ease the testing weight loss drugs.
MicroRNA Pathway Could Lead to New Avenues for Leukemia Treatment
Cancer researchers at the University of Cincinnati have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Doubling Down on Dengue
HMS researchers have discovered two ways a compound blocks dengue virus.
Soy Shows Promise as Natural Anti-Microbial Agent
Researchers from University of Guelph show that soy isoflavones and peptides could be used to reduce microbial contamination of food.
AstraZeneca to Sequence 2 Million Genomes in Search for New Drugs
Company launches integrated genomics approach which aims to transform drug discovery and development.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!