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Hepregen Launches First Dual-Species HepatoPac™ DMPK Assay Kits

Published: Wednesday, September 25, 2013
Last Updated: Tuesday, September 24, 2013
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Rat and human liver cells on a single tissue culture plate designed for high efficiency data collection.

Hepregen Corporation has announced the commercial launch of the Company's first application-oriented, dual-species HepatoPac™ kit designed specifically for use in metabolite identification and profiling.

Each kit contains one standard 24-well tissue culture plate, half containing micro-patterned human hepatocytes, and the other half containing micro-patterned rat hepatocytes (available in Wistar-Hahn or Sprague-Dawley strains).

The hepatocytes on these plates from both species remain fully functional for up to two months. These unique dual-species kits provide customers with a plug-in-ready product, designed for use in evaluating metabolite production in a discovery or development setting, or in any case where a quick comparative answer is beneficial.

Dr. Vincent Zurawski, Hepregen's chief executive officer stated, "The incredible flexibility of our HepatoPac™ assay systems allows Hepregen to provide customers with a variety of cost-effective options for generating predictive and mechanistic data regarding metabolite identification and profiling."

He added, "The launch of this new dual-species product represents another way in which Hepregen is responding to customer needs. Data collected from two species simultaneously in a single experiment, especially when one or just a few compounds need to be evaluated rapidly, provides the highest efficiency approach to predicting likely in vivo metabolic outcomes in the laboratory."

Jack McGeehan, Hepregen's vice president of operations, added, "Our new dual-species product is a perfect fit for both smaller pharmaceutical companies that are testing a limited number of compounds, or DMPK groups within larger companies who support program teams in need of quick answers to questions regarding likely best approaches to preclinical evaluation. Our new HepatoPac™ kit can provide answers that will support clinical trial design or approaches to toxicokinetic testing."

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