Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

3D Biomatrix and Cayman Chemical Partner

Published: Monday, November 25, 2013
Last Updated: Monday, November 25, 2013
Bookmark and Share
Companies have partnered to develop and supply a novel assay kit for measuring the viability of cells growing in three-dimensional (3D) spheroids.

3D Biomatrix announced that they have collaborated with Cayman Chemical to develop and supply a new assay kit for measuring the viability of 3D spheroids. The kit, Perfecta3D® Cell Viability Kit, is one of the first viability assays optimized for 3D cell culture.

Researchers have long tested drug compounds and other factors affecting cell growth in two-dimensions (2D), but 2D cell cultures do not accurately represent how cells behave in the body. 3D cell cultures allow researchers to recapitulate these characteristics in vitro, providing a more physiologically-relevant model. 3D Biomatrix’s Perfecta3D Hanging Drop Plates facilitate the consistent and controllable growth of small spherical 3D clusters called spheroids in a well-plate format. Researchers can then test compounds and other factors in a 3D environment that reflects the human body.

The new Perfecta3D 3D Cell Viability Kit provides an easy-to-use format for studying cell proliferation in spheroids formed in the Hanging Drop Plates. The assay, based on the enzymatic cleavage of the tertrazolium salt WST-1 to formazan by cellular mitochondrial dehydrogenases in viable cells, will allow investigators to screen drug candidates involved in cell cycle regulation in a 3D format.

“Our new 3D Cell Viability Assay Kit provides researchers with a solution for 3D cell culture and analysis,” said 3D Biomatrix CEO Laura Schrader. “As Cayman and 3D Biomatrix are leaders in their respective fields, researchers can be confident they are using reagents that have been specifically optimized for their needs in 3D cell culture.”

Jeff Johnson, Vice President of Biochemistry at Cayman Chemical says, “The 3D Biomatrix Perfecta3D Hanging Drop Plate is adding greater versatility to our growing line of cell-based assays. We are excited about the collaboration and the impact it will have on cell biology research.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,900+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

3D Biomatrix Announces Allowance of U.S. Patent
Cell culture technology uniquely addresses 3D spheroid and embryoid body growth challenges.
Thursday, February 06, 2014
Scientific News
Stem Cells in Drug Discovery
Potential Source of Unlimited Human Test Cells, but Roadblocks Remain.
Survey of New York City Soil Uncovers Medicine-Making Microbes
Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet.
'Lab on the Skin' for Sweat Analysis
Northwestern University researchers develop a low-cost wearable electronic device that collects and analyzes sweat for health monitoring.
Toxoplasma’s Balancing Act Explained
Parasite’s method of rewiring our immune response leads to novel tool for drug tests.
Cancer Signaling Pathway Illuminating Way To Therapy
Researchers refine a pro-growth signalling pathway, common to cancers, that can kill cancer cells while leaving healthy cells unharmed.
Breast Cancer Cells Starve for Cystine
Depriving triple negative breast cancer, a treatment-resistant form of breast cancer, of cystine results in cancer cell death.
T Cell Channel Could Be Targeted to Treat Cancers
Researcher identify ion-channel found within T cells that could be targeted to reduce development of neck and head cancers.
Novel Urine Test to Predict High-Risk Cervical Cancer
Preliminary studies affirm accuracy and potential cost savings to screen for virus-caused malignancy.
Biomarker Guiding Cancer Therapy
Biologists link levels of Mena protein to breast cancer cells’ sensitivity to chemotherapy.
Protein Array Can Pinpoint Cancer Biomarker
A novel detection method for the detection of glycoproteins has been developed.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!