Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Improving Accuracy, Productivity and Relevancy of Cell Based High Throughput Assays

Published: Monday, December 16, 2013
Last Updated: Sunday, December 15, 2013
Bookmark and Share
Launch of new Alvetex®Scaffold 3D cell culture plates from AMSBIO.

AMSBIO has announced the launch of a 384-well version of the popular Alvetex®Scaffold cell culture plates. The new Alvetex®Scaffold 3D cell culture plates provide biopharmaceutical companies with a new tool to improve the predictive accuracy, productivity and biological relevance of their cell based high throughput testing.

“We are excited about extending the application of 3D cell culture to high throughput laboratories and groups who need to test larger numbers of parameters with cells in a 3D environment. We have seen excellent uptake of the Alvetex®Scaffold 96 plates but customers have been asking for some time when we will help them do more with 3D cell culture” said Alex Sim, President of AMSBIO.

“Our customers have been delighted with the incredibly simple workflow and the ease of analysis when using Alvetex® 3D cell culture products” he added.

A typical application for this new product is in cancer cell cytotoxicity testing. The Alvetex®Scaffold 384-well plates allow scientists to grow tumour cells in a way that better mimics the way these cells grow in vivo.

It is then very simple to test the cytotoxic effect of novel or existing anti-cancer compounds using standard cell health assays such as MTT, XTT, extracellular oxygen consumption and many others.

Researchers can then easily retrieve RNA and protein from the drug treated cells to study mechanism of action and look for biomarkers. Alvetex®Scaffold plates work seamlessly with liquid handling robotic systems further enhancing the high throughput potential of users cell based testing.

Alvetex®Scaffold is also available through AMSBIO in other formats including a 12-well culture plate, 24-well culture plate, 96 well plate, 6-well and 12-well inserts. These formats enable scientists to construct different 3D cell culture models and assays.

These include screening of novel drugs / drug combinations on 3D culture and co-culture models, co-culture to study cell-cell or cell-matrix interactions, the growth of cells at the air-liquid interface and the long-term culture of cells.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,300+ scientific posters on ePosters
  • More than 4,900+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Ready-to-Use Tagged cDNA Clones
Available from AMSBIO TrueORF®cDNA clones are tagged cDNA clones for protein studies.
Monday, June 01, 2015
AMSBIO Publishes Comprehensive Cell Culture Handbook
Extensive 48-page handbook is intended for research scientists looking to culture cells in more physiologically relevant environments.
Friday, April 04, 2014
AMSBIO & Sanguine Biosciences Announce Distribution Agreement
Agreement to distribute and support AMSBIO’s products and services throughout Europe.
Friday, August 23, 2013
Scientific News
Gene Terapy for Muscle Wasting Developed
New gene therapy could save millions of people suffering from muscle wasting disease.
Detecting Alzheimer's with Smell Test
Odour identification test may offer low-cost alternative for predicting cognitive decline and detecting early-stage Alzheimer’s disease.
Fighting Cancer Through Protein Pathways
Researchers have found a new drug target within a protein production pathway critical to regulating growth and proliferation of cells.
Mutations in DNA-Repair Genes Found in Advanced Prostate Cancers
New findings indicate that nearly 12% of male advanced prostate cancer sufferers have inherited mutation in DNA-repair genes.
Molecule May Affect Gaucher, Parkinson's Disease
Research has identified a molecule that restores activity of a dysfunctional enzyme linked to Gaucher and Parkinson's disease.
Targeting BRAF Mutations in Thyroid Cancer
Treating metastatic thyroid cancer patients harboring a BRAF mutation with vemurafenib showed anti-tumor activity in a third of patients.
Plant Compounds Fight Together Against Colon Cancer
Research shows treating colon cancer cells with curcumin, then silymarin is more effective than treatment with each individually.
New Centre Offers Ultra-Speed Protein Analysis
UW-Madison researchers to establish development centre for next-gen protein measurement technologies.
Drug Candidates Reduce Abnormal Protein Production
New drug candidates improve cell ability to catch miss-folded proteins that could cause deadly diseases.
Supercomputing and Drug Discovery
New biotech company uses supercomputer simulations to speed up drug discovery and biotech molecule development.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!