Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

InSphero to Distribute Dainippon Screen Imager for Rapid Profiling of 3D Microtissues

Published: Tuesday, April 08, 2014
Last Updated: Tuesday, April 08, 2014
Bookmark and Share
The Cell'iMager, to be marketed in the US and Europe, simplifies growth and morphological profiling of 3D microtissues.

InSphero AG and Dainippon Screen (Kyoto, Japan) announced today they have reached a
distribution agreement for InSphero to begin marketing Dainippon Screen's Cell'iMager in North
America and Europe. Dainippon Screen selected InSphero based on their in-depth know-how
pertaining to 3D microtissue biology and applications. The CelriMager is fully compatible with
InSphero's GravityTRAPTm 3D microtissue assay platform and other 3D-cell culture plates,
providing rapid, robust profiling of microtissue growth and morphology.

3D tumor microtissues or spheroids are increasingly used in drug discovery and development as
a more representative biological model for testing drug sensitivity and efficacy. Size and
morphology are important determinants to evaluate the biological behavior of 3D microtissues,
particularly in development of anti-cancer drugs, where monitoring cell growth is a particularly
critical endpoint. High-throughput, accurate assessment of 3D microtissue size and growth in
these applications is currently limited by sequential, time-consuming and often manual optical
measurements.

The innovative CelriMager's high-resolution scanning optics provide rapid direct measurement
of multiple endpoints, including microtissue diameter, area, pseudo-volume, and circularity at a
resolution of up to 9600 dpi. The system can analyze four 96- or 384-well plates in a single run,
in as little as one minute per plate, enabling fast and label-free visualization of even small size
differences. The scanner software is tailored for the analysis of 3D microtissues, allowing
adjustment of parameters such as focal plane, minimum and maximum object size, scan area,
and resolution for developing protocols specific to a given tissue type or assay.
The instrument is already broadly used in Japan and is now available in North America and
Europe through InSphero's experienced sales team.

InSphero CEO and co-founder Dr. Jan Lichtenberg sees the agreement as an exciting next step
toward making InSphero a total solution provider for the 3D cell culture marketplace. "Adding
the Cell3iMager to our portfolio gets us closer to offering our customers a complete set of
solutions for 3D cell based assays — from the assay-ready 3D cell model, to assay reagents and
instruments for endpoint analysis."

Mr. Kunihisa Hashimoto, General Manager of Dainippon Screen's Imaging and Solutions
Division, noted the agreement with InSphero is also a major step for Dainippon Screen.
"Combining InSphero's GravityTRAPTm plates and microtissues with the imaging technology of
our Cell'iMager is sure to streamline and simplify research using 3D tissue cultures. We are
excited to leverage InSphero's expertise in the 3D marketplace to help bring our innovative
imaging system to North America and Europe."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,900+ scientific posters on ePosters
  • More than 4,200+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

InSphero Expands Global Availability of its Patented 3D Cell Culture Platforms
PerkinElmer named as exclusive distributor of InSphero 3D culture technology.
Thursday, August 06, 2015
InSphero AG Secures CHF 20 Million Series C Financing
3D cell culture company gains new long-term investor to fuel expansion of global operations and product portfolio.
Wednesday, July 15, 2015
InSphero AG Secures CHF 20 Million Series C Financing
Leading 3D cell culture company gains new long-term investor to fuel expansion of global operations and product portfolio.
Tuesday, July 14, 2015
InSphero Publishes 3D Tumor-Stroma Model for Non-Small Cell Lung Cancer
PLOS One article delivers promising co-culture method to mimic tumor microenvironment, demonstrating potential for biomarker and drug discovery.
Thursday, April 24, 2014
InSphero Announces Collaboration with NCATS
Study to characterize 460 NCATS anti-cancer agents in 3D tumor models generated using InSphero technology.
Friday, March 21, 2014
Scientific News
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Visualizing a Cancer Drug Target at Atomic Resolution
Using cryo-electron microscopy, researchers were able to view, in atomic detail, the binding of a potential small molecule drug to a key protein in cancer cells.
Honey’s Potential to Save Lives
The healing powers of honey have been known for thousands of years.
3-D Printed Lifelike Liver Tissue for Drug Screening
A team led by engineers at the University of California, San Diego has 3D-printed a tissue that closely mimics the human liver's sophisticated structure and function. The new model could be used for patient-specific drug screening and disease modeling.
Cytoskeleton Crew
Findings confirm sugar's role in helping cancers survive by changing cellular architecture.
Biomarker for Recurring HPV-Linked Oropharyngeal Cancers
A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at the Johns Hopkins University.
Valvena, GSK Sign New R&D Collaboration
Valneva to supply process development services for EB66® -based Influenza vaccines.
Light Signals from Living Cells
Fluorescent protein markers delivered under high pressure.
Cellular 'Relief Valve'
A team led by scientists at The Scripps Research Institute (TSRI) has solved a long-standing mystery in cell biology by showing essentially how a key “relief-valve” in cells does its job.
Genomic Signature Shared by Five Types of Cancer
National Institutes of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!