Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
Become a Member | Sign in
Home>News>This Article

New XFe96 Spheroid Microplate from Seahorse Bioscience

Published: Tuesday, April 22, 2014
Last Updated: Thursday, April 24, 2014
Bookmark and Share
The microplate enables functional, metabolic measurement of in vitro tumor spheroids.

This unique 96-well plate features geometry that enables functional, metabolic measurements of individual spheroids for the study of three-dimensional cell culture, which more closely mimics in vivo conditions. Of particular importance for tumor studies, the real-time metabolism of multicellular spheroids can now be analyzed and used for evaluating the metabolic response to therapeutic agents.

“Our customers indicated a need for three-dimensional assay capability but they did not have a measurement tool until now,” explains Brian P. Dranka, Ph.D., manager of biology for Seahorse Bioscience. “Using the XFe96 Spheroid Microplate and the XFe96 Extracellular Flux Analyzer, scientists can now obtain sensitive and reproducible data from individual spheroids with high specificity.”

The XFe96 Extracellular Flux Analyzer simultaneously measures the two major energy-producing pathways within the cell ¬¬– mitochondrial respiration and glycolysis – in a microplate, in real time. The XFe96 Analyzer and Stress Test Kits standardize the measurement of mitochondrial function and glycolysis. The addition of the XFe96 Spheroid Microplate further advances the study of cell metabolism, helping scientists better understand the connection of physiological traits of cells with genomic and proteomic data. This knowledge will generate new insights into cell metabolism and mitochondrial function, leading to a greater understanding and new treatments of diseases including cancer.

The XFe96 Spheroid FluxPak contains six cartridges, six microplates and calibrant. The new plates will be ready for orders and shipment at the beginning of May.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
World’s First Therapeutic Venom Database
Open-source library describes nearly 43,000 effects on the human body.
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Potential Persistent Tuberculosis Treatment
Researchers have discovered several first-in-class compounds that target hidden TB infections by attacking a critical process the bacteria use to survive in the hostile environment of the lungs.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
The Do’s and Don’ts of SPR Experiments
Surface Plasmon Resonance (SPR) is a technique that is becoming more widely used, particularly by anyone who wants to obtain accurate on (association) and off (dissociation) rates for biomolecular binding.
Long-Sought Protein Sensor for the ‘Sixth Sense’ Discovered
In a study led by scientists from The Scripps Research Institute (TSRI)the sensor protein for propioception has been identified.
New Anti-Malarial Drug Screening Model
University of South Florida researchers demonstrate novel chemogenomic profiling to identify drug targets for the most lethal strain of malaria.
Shedding Light on “Dark” Cellular Receptors
UNC and UCSF labs create a new research tool to find homes for two orphan cell-surface receptors, a crucial step toward finding better therapeutics and causes of drug side effects.

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos