Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Biodesign Institute, Thermo Fisher Partner on $9M Radiation Test

Published: Wednesday, June 04, 2014
Last Updated: Wednesday, June 04, 2014
Bookmark and Share
Partnership enters a new, $9M phase of a project to produce a diagnostic test to rapidly measure an individual’s level of absorption of ionizing radiation.

The project is part of a potential $31.2 million in total funds authorized by the Biomedical Advanced Research and Development Authority (BARDA), a federal agency within the Office of the Assistant Secretary for Preparedness and Response of the U.S. Department of Health and Human Services. The project is a collaboration with Life Sciences Solutions at Thermo Fisher Scientific and utilizes the Life Technologies brand of qPCR (quantitative polymerase chain reaction) instruments for analysis of gene expression.

“We are proud to be moving forward in this ambitious, challenging project that combines ASU’s considerable research strengths in biomarkers with Thermo Fisher’s expertise in the product commercialization process,” said Joshua LaBaer, director of the Biodesign Institute’s Virginia G. Piper Center for Personalized Diagnostics.  “Our research team’s ultimate goal is to translate our discoveries for development of an automated high-throughput system for radiation biodosimetry that is capable of processing a high volume of blood samples per day for gene expression analysis.”

“We are very pleased that our colleagues at Arizona State University selected the Life Technologies brand of qPCR instruments for this important work to protect public safety,” said Chris Linthwaite, head of Genetic Systems Division, Research Platforms at Thermo Fisher. “The project represents a novel approach to deliver fast and accurate measures of absorbed radiation using molecular detection technology.” 

Currently, no rapid, FDA cleared high-throughput system exists to measure the radiation dose absorbed by individuals within a large population. Of the eleven project teams launched in 2010, the ASU group is one of six continuing development of a medical device to address this application.

The Biodesign Institute at ASU is designing a multi-gene assay panel and collaborating with Thermo Fisher to develop a real-time quantitative PCR-based assay system to rapidly assess absorbed radiation dose.  The Project is entering a $9M contract option to optimize the biomarker assay and platform workflow to prepare for testing needed to seek regulatory clearance for the assay from the U.S. Food and Drug Administration.

According to members of the ASU Biodesign Institute team, Thermo Fisher will lead the FDA submission process for the assay panel utilizing its PCR platforms that are currently listed with the FDA.

“As part of the project, the Biodesign Institute has developed a high-quality, biomarker discovery core competency utilizing next generation sequencing and gene selection algorithms that can reproducibly identify and select biomarkers.  Our process includes quality control standards and can be applied to many other medical challenges for research, diagnosis or development of a therapeutic,” said Kristin Gillis, senior scientific project manager.  

Collaborators to the team, along with Biodesign Institute biomarker research expert Dr. Joshua LaBaer, director of the institute’s Virginia G. Piper Center for Personalized Diagnostics, include Sally Amundson, PhD, at Columbia University Medical Center, who has extensive experience in researching radiation responsive genes, and ASU’s strategic partnership with Mayo Clinic, where Dr. William Wong will provide critical access to patient clinical samples needed for biomarker development. 


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo, Nuclea Biotechnologies Collaborate to Develop Diabetes Markers
Companies pooling their expertise to develop novel multiplexed research methods for high-throughput quantification of native insulin and its therapeutic analogs.
Monday, June 02, 2014
Thermo Fisher Scientific Announces 4th Annual Cellome Award Winner
Vishal Deshmukh, Scripps Institute to accept award for excellence in the application of high content technology in Multiple Sclerosis research.
Wednesday, February 26, 2014
Thermo Reports 6% Q4 Revenue Growth
Thermo Fisher Scientific Inc. reported its financial results for the fourth quarter and full year ended December 31, 2013.
Friday, January 31, 2014
One Lambda Receives CE Mark Approval for C1qScreen
Assay cited in New England Journal of Medicine for use in determining impact on kidney graft survival.
Tuesday, November 19, 2013
Thermo Scientific Selected to Supply Maybridge Fragment Library for Key Research
Recommended for use by renowned fragment library design expert.
Tuesday, February 05, 2013
Record Revenues for Thermo Fisher Scientific
Revenue for the quarter grew 6% to $3.26 billion in 2012, versus $3.09 billion in 2011.
Thursday, January 31, 2013
Thermo Scientific Enters into a Long-Term Agreement with Fujirebio
Combination of Thermo Scientific B•R•A•H•M•S PCT assay and Lumipulse platforms to test patients suspected of having sepsis.
Thursday, November 22, 2012
Thermo Fisher Scientific Introduces Guide to Good Washing Practice
The online guide is designed to provide detailed guidance on obtaining secure and reliable performance with every use of the Thermo Scientific Wellwash microplate washers.
Thursday, October 21, 2010
Thermo Fisher Scientific Launches Maybridge Ro3 Diversity Fragment Library
Diverse set of 1,500 molecules engineered for high-quality fragment screening-based programmes.
Tuesday, July 06, 2010
Thermo Fisher Scientific Names Recipients of RNAi Discovery Grants
More than $400,000 in RNAi screening tools awarded to advance biomedical research and drug discovery.
Friday, November 06, 2009
Thermo Fisher Scientific Signs Agreement to Acquire B.R.A.H.M.S. AG
Company acquires provider of specialty in-vitro diagnostic tests for $470 million USD.
Monday, September 07, 2009
Thermo Fisher Scientific to Showcase Innovative Mass Spectrometry Solutions at IMSC 2009
Company will showcase a variety of mass spectrometry software and hardware solutions to deliver improved analytical performance.
Monday, September 07, 2009
Thermo Fisher Scientific Implements LIMS for the Food and Environment Research Agency
Fera uses Thermo Scientific Nautilus to manage critical laboratory data and processes.
Thursday, September 03, 2009
Thermo Fisher Scientific Goes Global with Food Safety Seminar Series
The global seminar program will take place across the U.S., Canada, Europe, Southeast Asia and Japan to explore global perspectives on food safety.
Friday, August 28, 2009
Thermo Fisher Scientific Celebrates 30th Anniversary of the Thermo Scientific Multiskan
The company has invited the researchers are to join the search for the oldest multiskan in use.
Thursday, June 04, 2009
Scientific News
Liquid Biopsies: Utilization of Circulating Biomarkers for Minimally Invasive Diagnostics Development
Market Trends in Biofluid-based Liquid Biopsies: Deploying Circulating Biomarkers in the Clinic. Enal Razvi, Ph.D., Managing Director, Select Biosciences, Inc.
Lab-on-a-Chip Offers Promise for TB and Asthma Patients
A device to mix liquids using ultrasonics is the first and most difficult component in a miniaturized system for low-cost analysis of sputum from patients with pulmonary diseases such as tuberculosis and asthma.
Protein Related to Long Term Traumatic Brain Injury Complications Discovered
NIH-study shows protein found at higher levels in military members who have suffered multiple TBIs.
Urine Proteins Point to Early-Stage Pancreatic Cancer
A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, researchers at the BCI have shown.
Researcher Discovers Trigger of Deadly Melanoma
New research sheds light on the precise trigger that causes melanoma cancer cells to transform from non-invasive cells to invasive killer agents, pinpointing the precise place in the process where "traveling" cancer turns lethal.
Crystal Clear Images Uncover Secrets of Hormone Receptors
NIH researchers gain better understanding of how neuropeptide hormones trigger chemical reactions in cells.
New Tool Uses 'Drug Spillover' to Match Cancer Patients with Treatments
Researchers have developed a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker (KAR) predicts what genetics are truly driving the cancer in any population of cells and chooses the best "kinase inhibitor" to silence these dangerous genetic causes of disease.
HIV Susceptibility Linked to Little-Understood Immune Cell Class
High levels of diversity among immune cells called natural killer cells may strongly predispose people to infection by HIV, and may be driven by prior viral exposures, according to a new study.
Sweet Revenge Against Superbugs
A special type of synthetic sugar could be the latest weapon in the fight against superbugs.
Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support
A new study reveals a protein’s critical – and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!