Corporate Banner
Satellite Banner
Biomolecular Screening
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

CCS Cell Culture Service and Cytocentrics Agree Cooperation in the Field of Cell Line Development

Published: Monday, October 06, 2008
Last Updated: Monday, October 06, 2008
Bookmark and Share
The agreement is aimed at the development of electrophysiologically optimized ion channel cell lines which allow a reliable testing of substances and drugs.

Biotechnology companies CCS Cell Culture Service GmbH and Cytocentrics AG has announced the signing of a research and license agreement. The aim of the cooperation is to develop electrophysiologically optimized ion channel cell lines which allow a reliable testing of substances and drugs.

The pharmaceutical industry depends on suitable in-vitro test methods for preclinical drug screening and safety pharmacology testing. Over recent years the automated patch clamp technology has established itself in this field. However, in many cases the application of conventional recombinant cell lines results in low data quality.

The cooperation paves the way for the production of cell lines generating reliable and reproducible data in automated patch clamp systems. CCS brings its expertise in the production of recombinant cell lines into this partnership and Cytocentrics will focus on electrophysiological optimization.

"Combining the core competences of both companies will set new standards in the development of new drugs", explains Dr. Oliver Klotzsche, managing director and co-founder of the CCS Cell Culture Service GmbH. "Both companies have very high quality standards. The long experience of both companies allows professional work to be carried out in compliance with the high standards required by the pharmaceutical industry".

In detail the cooperation agreement comprises the production and optimization of cell lines expressing pharmacologically relevant ion channels. The first two cell lines hERG-HEK 293 and hNav1.5-CHO have recently become available for purchase.

“In our service sector for safety pharmacology testing, we are already successfully using cell lines which have been jointly developed", explains Dr. Christa Nutzhorn, President of Cytocentrics AG. “Customers from the pharmaceutical industry sector are completely satisfied with the high quality of measuring data."

Each batch of cells is subjected to quality controls prior to delivery. Quality standards refer to the seal rate, rate of whole-cell recordings, stability and existence of a homogenous flow. Customers can either acquire a license for a cell line or order so-called "Instant Cells", rendering unnecessary the time consuming cultivation of cells. These cells are ready-to-use in an assay within 15 minutes after defrosting.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Penn State, TB Alliance, and GSK Partner To Discover New Treatments For TB
A new collaboration between TB Alliance, GSK, and scientists in the Eberly College of Science seeks to find new small molecules that can be used to create antibiotics in the fight against tuberculosis (TB).
Molecular Map Provides Clues To Zinc-Related Diseases
Mapping the molecular structure where medicine goes to work is a crucial step toward drug discovery against deadly diseases.
Platelets are the Pathfinders for Leukocyte Extravasation During Inflammation
Findings from the study could help in the prevention and treatment of inflammatory pathologies.
Genetic Research Can Significantly Improve Drug Development
With drug development costs topping $1.2bn (£850 million) to get a single treatment to the point it can be sold and used in the clinic, could genetic analysis save hundreds of millions of dollars?
New Method Opens Door to Development of Many New Medicines
Findings from TSRI reveal human proteins are better drug targets than previously thought.
Diagnosing Systemic Infections Quickly, Reliably
Team develop rapid and specific diagnostic assay that could help physicians decide within an hour whether a patient has a systemic infection and should be hospitalized for aggressive intervention therapy.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Blood Test That Detects Early Alzheimer’s Disease
A research team, led by Dr. Robert Nagele from Rowan University School of Osteopathic Medicine and Durin Technologies, Inc., has announced the development of a blood test that leverages the body’s immune response system to detect an early stage of Alzheimer’s disease – referred to as the mild cognitive impairment (MCI) stage – with unparalleled accuracy.
A New Approach to Chemical Synthesis
Communesins, originally found in fungus, could hold potential as cancer drugs.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!