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Drug Discovery

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Functional Screening of recombinant CHO-M1 cells using the PHERAstar from BMG LABTECH

Poster

Published: August 5, 2009

Functional Screening of recombinant CHO-M1 cells using the PHERAstar from BMG LABTECH content piece image

Functional screening of single cell clones was achieved using the HTRF® IP-One assay. The HTRF® assay from Cisbio proved to be a fast and reliable method to directly screen a large number of stable transfected single cell clones. Carbachol dose response curves with fresh cells from a growing culture and frozen instant cells showed similar results for EC50 and signal-to-blank values.