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Promising Class of New Cancer Drugs Cause Memory Loss in Mice
New findings from The Rockefeller University suggest that the original version of BET inhibitors causes molecular changes in mouse neurons, and can lead to memory loss in mice that receive it.
Electrical Control of Cancer Cells
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Inflammation Linked to Colon Cancer Metastasis
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Structural Discoveries Could Aid in Better Drug Design
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Determining the Age of Fingerprints
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Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies
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Surprising Mechanism Behind Antibiotic-Resistant Bacteria Uncovered
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Tissue Bank Pays Dividends for Brain Cancer Research
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Researchers Publish Landmark “Basket Study”
Researchers from Memorial Sloan Kettering Cancer Center (MSK) have announced results from the first published basket study, a new form of clinical trial design that explores responses to drugs based on the specific mutations in patients’ tumors rather than where their cancer originated.

Label-Free Binding Analysis Trends 2014
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The main objectives were to comprehensively document current experience of and future interest in investigating biomolecular interactions and binding analysis using LF technologies. The study also examined in detail the changing market landscape, application areas and future purchasing plans.

The report is a source of valuable information for vendors developing LF binding analysis systems, and provides the latest market information on this rapidly changing area.

Equal emphasis was given to soliciting opinion from Pharma, Biotech and Academic Research segments, active in either small molecule drug discovery or protein and biologics characterization.

The survey looked at the following aspects of LF binding analysis as practiced today (2014) and in some cases as predicted for the future (2016): areas where biomolecular binding analysis is primarily used; techniques used to assess binding interactions; how respondent’s research objectives are aided by LF technology; classification that most closely describes an LF binding assay; vendor’s LF technologies currently available in respondent’s lab; most recognizable LF instrument brands; current perception of different LF instrument suppliers; the most common limitation experienced using an LF assay approach: applications that LF binding assays are best suited for; application areas where LF binding assays are expected to gain most popularity over coming years; processes which could most benefit from the use or expanded use of LF binding assays; integration of any LF instruments/devices used for binding analysis into automated robotic systems; importance given to some application capabilities when purchasing a new LF system for binding analysis; attributes of a new label-free binding analysis system that impact a purchasing decision; what influences the timing of a decision to purchase a LF system; likelihood of purchasing a new LF instruments for binding analysis over the coming years; the primary use of respondent’s next LF instrument purchase; the top two vendors from which respondents are most likely to purchase a new LF instrument; annual capex and consumable budgets for LF binding analysis; resources most relied upon to learn about/gather information on new LF technologies and assays; conferences attended in the last 12 months; publications subscribed to, regularly read or visited online; and any unmet needs in LF binding analysis.


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