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Comparison of Photina Luminescent Calcium Mobilization Assays on both the FlexStation® 3 and FLIPRTETRA® Systems
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Molecular Devices

G-protein coupled receptors (GPCRs) represent one of the most important therapeutic targets in drug discovery research. GPCRs are membranelocalized proteins that play an important role in cell signaling. When a receptor is activated by a ligand, the conformation of the receptor is modified, activating G-proteins inside the cell. An active G-protein has the potential to induce various cascades of intracellular messengers, including calcium.

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