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Potential “Good Fat” Biomarker
New method to measure the activity of energy consuming brown fat cells could ease the testing weight loss drugs.
MicroRNA Pathway Could Lead to New Avenues for Leukemia Treatment
Cancer researchers at the University of Cincinnati have found a particular signaling route in microRNA (miR-22) that could lead to targets for acute myeloid leukemia, the most common type of fast-growing cancer of the blood and bone marrow.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Doubling Down on Dengue
HMS researchers have discovered two ways a compound blocks dengue virus.
Soy Shows Promise as Natural Anti-Microbial Agent
Researchers from University of Guelph show that soy isoflavones and peptides could be used to reduce microbial contamination of food.
AstraZeneca to Sequence 2 Million Genomes in Search for New Drugs
Company launches integrated genomics approach which aims to transform drug discovery and development.
Unique Model for Studying ALS
Unique mouse model will allow researchers to better study the genetic origins and potential treatments of ALS.
Targeting an ‘Undruggable’ Cancer Gene
RAS genes are mutated in more than 30 percent of human cancers and represent one of the most sought-after cancer targets for drug developers.
Biomarkers for Profiling Prostate Cancer Patients
Exiqon A/S has announced the publication of validation of prognostic microRNA biomarkers for the aggressiveness of prostate cancer in independent cohorts.
Improving Engineered T-Cell Cancer Treatment
Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list."
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Biotechnology Journal
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Biotechnology Journal is the new, international resource for both biotechnology researchers and professionals in related disciplines. Fully comprehensive in its scope, the journal publishes strictly peer-reviewed papers covering novel aspects and methods in all areas of biotechnology. Special attention is also paid to the public, legal, ethical and cultural aspects of biotechnological research in the Forum section. Most issues are devoted to a special topic, providing the latest comprehensive information on the most crucial areas of research and technological advances.

Alongside each highlighted topic, the journal contains original papers in the form of research articles, short communications and technical reports, illustrating the latest research results. BTJ welcomes submission of papers in areas including DNA/protein engineering, all -omics fields (genomics, proteomics, metabolomics, systems biology etc.), bioinformatics (algorithms and modeling), imaging, analytical biotech (sensors/detectors for analytes/macromolecules), plant/agricultural, food or environmental biotechnology, health and therapeutical biotechnology (including antisense/siRNAs, enzymes, peptides ...), regenerative medicine (stem cells, tissue engineering and biomaterials), translational immunology (antibody engineering, xenotransplantation, T-cell therapies), and biosafety or biosecurity.

BTJ promotes a special emphasis on:

    * Systems Biotechnology
    * High-Throughput and Microarray Technologies
    * Synthetic Biology and Metabolic Engineering
    * Nanobiotechnology
    * Translational Biotechnology and Applied Microbiology
    * Methods and Advances
    * Biosafety, biotech ethics, science communication

In particular, BTJ welcomes submissions on

Systems Biology/ Bioinformatics: Overview and interplay between biological system components and their functional implications (for example enzymes and metabolites in a metabolic pathway). Computational analysis of all topics mentioned below (modeling, algorithms, data deconvolution).

Synthetic Biology: The design and construction of new biological parts, devices and systems; re-design of natural biological systems for useful purposes.

Nanobiotech/ Biomaterials: Nanomaterials for industrial (white) biotech, drug delivery therapeutics, biochips, micro- and nanofluidics, nanosensors, and nanosystems for imaging; engineering materials for biological application, molecular imprinting, and biomimetics.

Medicine/ Red Biotech/ Stem cells: Therapeutic cloning (somatic cell nuclear transfer), tissue engineering, xenotransplantation; DNA or RNA therapeutics (gene therapy, targeting, immunogenicity); vaccines and applied immunology (Ab engineering, T-cell therapies, therapies exploiting innate immunity, antigen delivery vectors and approaches; viral or non-viral strategies for drug delivery.

Mammalian Biotech/ Genetics: Manipulating gene structure and control of gene expression; transgenic animals, knockouts, reproductive cloning, biopharmaceutical and enzyme production, transgene targeting and expression strategies.

Metabolic Engineering: Genetic manipulation of species of interest to modify or allow the production of a commercially or therapeutically relevant compound.

Biocatalysis: Evolution and protein design (antibodies, enzymes, drugs ...).

White/Industrial Biotechnology: Chemical synthesis by bacteria, yeast or other organisms, use of enzymes as industrial catalysts, biopharmaceutics, biofuels.

Omics, Analytical Biotech, Biosensors: (Meta)genomics, structural genomics, gene function analysis (e.g., arrays, SAGE), pharmacogenomics (SNPs), gene structure analysis, chemogenomics, proteomics (e.g., mass spectrometry, yeast two hybrid, arrays and chips, NMR, SPR), metabolomics (chromatography, mass spectrometry). Analytical methods and systems for monitoring research, development and production of biotechnological products.

Methods: Technical aspects and practical protocols for all biotech applications; Expression systems in mammalian, insect, bacterial, fungal or plant cells; Screening methods; Novel organism/cell/molecular imaging techniques, high throughput imaging tools for drug screening, fluorescence microscopy, electron microscopy/tomography, confocal imaging ...

Biochemical Engineering/ Downstream Processing: Chemical engineering aspects of biological processes from primary material to product recovery; separation, purification, and packaging after fermentation or bioconversion.

Plant Biotechnology: Crop improvement (resistance to stress, disease, pests), nutraceuticals, forest biotech, plant vaccines or bioreactors, biosecurity and gene-containment strategies, bioenergy, microbial biodegradation, food biotech, environmental biotech: bioremediation, biomining, phytoremediation, monitoring.

Food Biotechnology: Application of microbiology and metabolic aspects to food and beverage systems; food safety and pathogens, food fermentation, food bioactive compounds.

Biosafety, Biotech Ethics, Science Communication.

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