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High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
University of Edinburgh, Selcia Achieve Key Milestones in Drug Development Program
Scientists from the University of Edinburgh, working with Selcia, have successfully passed the 20-month milestone targets of a 30-month Wellcome Trust SDDi £2.5 million project to design novel treatments for sleeping sickness.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
World’s First Therapeutic Venom Database
Open-source library describes nearly 43,000 effects on the human body.
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Potential Persistent Tuberculosis Treatment
Researchers have discovered several first-in-class compounds that target hidden TB infections by attacking a critical process the bacteria use to survive in the hostile environment of the lungs.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
The Do’s and Don’ts of SPR Experiments
Surface Plasmon Resonance (SPR) is a technique that is becoming more widely used, particularly by anyone who wants to obtain accurate on (association) and off (dissociation) rates for biomolecular binding.
Long-Sought Protein Sensor for the ‘Sixth Sense’ Discovered
In a study led by scientists from The Scripps Research Institute (TSRI)the sensor protein for propioception has been identified.
New Anti-Malarial Drug Screening Model
University of South Florida researchers demonstrate novel chemogenomic profiling to identify drug targets for the most lethal strain of malaria.
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Biotechnology Journal
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Biotechnology Journal is the new, international resource for both biotechnology researchers and professionals in related disciplines. Fully comprehensive in its scope, the journal publishes strictly peer-reviewed papers covering novel aspects and methods in all areas of biotechnology. Special attention is also paid to the public, legal, ethical and cultural aspects of biotechnological research in the Forum section. Most issues are devoted to a special topic, providing the latest comprehensive information on the most crucial areas of research and technological advances.

Alongside each highlighted topic, the journal contains original papers in the form of research articles, short communications and technical reports, illustrating the latest research results. BTJ welcomes submission of papers in areas including DNA/protein engineering, all -omics fields (genomics, proteomics, metabolomics, systems biology etc.), bioinformatics (algorithms and modeling), imaging, analytical biotech (sensors/detectors for analytes/macromolecules), plant/agricultural, food or environmental biotechnology, health and therapeutical biotechnology (including antisense/siRNAs, enzymes, peptides ...), regenerative medicine (stem cells, tissue engineering and biomaterials), translational immunology (antibody engineering, xenotransplantation, T-cell therapies), and biosafety or biosecurity.

BTJ promotes a special emphasis on:

    * Systems Biotechnology
    * High-Throughput and Microarray Technologies
    * Synthetic Biology and Metabolic Engineering
    * Nanobiotechnology
    * Translational Biotechnology and Applied Microbiology
    * Methods and Advances
    * Biosafety, biotech ethics, science communication

In particular, BTJ welcomes submissions on

Systems Biology/ Bioinformatics: Overview and interplay between biological system components and their functional implications (for example enzymes and metabolites in a metabolic pathway). Computational analysis of all topics mentioned below (modeling, algorithms, data deconvolution).

Synthetic Biology: The design and construction of new biological parts, devices and systems; re-design of natural biological systems for useful purposes.

Nanobiotech/ Biomaterials: Nanomaterials for industrial (white) biotech, drug delivery therapeutics, biochips, micro- and nanofluidics, nanosensors, and nanosystems for imaging; engineering materials for biological application, molecular imprinting, and biomimetics.

Medicine/ Red Biotech/ Stem cells: Therapeutic cloning (somatic cell nuclear transfer), tissue engineering, xenotransplantation; DNA or RNA therapeutics (gene therapy, targeting, immunogenicity); vaccines and applied immunology (Ab engineering, T-cell therapies, therapies exploiting innate immunity, antigen delivery vectors and approaches; viral or non-viral strategies for drug delivery.

Mammalian Biotech/ Genetics: Manipulating gene structure and control of gene expression; transgenic animals, knockouts, reproductive cloning, biopharmaceutical and enzyme production, transgene targeting and expression strategies.

Metabolic Engineering: Genetic manipulation of species of interest to modify or allow the production of a commercially or therapeutically relevant compound.

Biocatalysis: Evolution and protein design (antibodies, enzymes, drugs ...).

White/Industrial Biotechnology: Chemical synthesis by bacteria, yeast or other organisms, use of enzymes as industrial catalysts, biopharmaceutics, biofuels.

Omics, Analytical Biotech, Biosensors: (Meta)genomics, structural genomics, gene function analysis (e.g., arrays, SAGE), pharmacogenomics (SNPs), gene structure analysis, chemogenomics, proteomics (e.g., mass spectrometry, yeast two hybrid, arrays and chips, NMR, SPR), metabolomics (chromatography, mass spectrometry). Analytical methods and systems for monitoring research, development and production of biotechnological products.

Methods: Technical aspects and practical protocols for all biotech applications; Expression systems in mammalian, insect, bacterial, fungal or plant cells; Screening methods; Novel organism/cell/molecular imaging techniques, high throughput imaging tools for drug screening, fluorescence microscopy, electron microscopy/tomography, confocal imaging ...

Biochemical Engineering/ Downstream Processing: Chemical engineering aspects of biological processes from primary material to product recovery; separation, purification, and packaging after fermentation or bioconversion.

Plant Biotechnology: Crop improvement (resistance to stress, disease, pests), nutraceuticals, forest biotech, plant vaccines or bioreactors, biosecurity and gene-containment strategies, bioenergy, microbial biodegradation, food biotech, environmental biotech: bioremediation, biomining, phytoremediation, monitoring.

Food Biotechnology: Application of microbiology and metabolic aspects to food and beverage systems; food safety and pathogens, food fermentation, food bioactive compounds.

Biosafety, Biotech Ethics, Science Communication.

Further Information


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